Iron Homeostasis in Azotobacter vinelandii

Iron is an essential nutrient for all life forms. Specialized mechanisms exist in bacteria to ensure iron uptake and its delivery to key enzymes within the cell, while preventing toxicity. Iron uptake and exchange networks must adapt to the different environmental conditions, particularly those that...

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Detalles Bibliográficos
Autores: Rosa-Núñez, Elena, Echávarri-Erasun, Carlos, Armas, Alejandro M., Escudero, Viviana, Poza-Carrión, César, Rubio, Luis M., González-Guerrero, Manuel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/340174
Acceso en línea:http://hdl.handle.net/10261/340174
Access Level:acceso abierto
Palabra clave:Biological nitrogen fixation
Nitrogenase
Iron–sulfur cluster
Iron transport
Iron nutrition
Descripción
Sumario:Iron is an essential nutrient for all life forms. Specialized mechanisms exist in bacteria to ensure iron uptake and its delivery to key enzymes within the cell, while preventing toxicity. Iron uptake and exchange networks must adapt to the different environmental conditions, particularly those that require the biosynthesis of multiple iron proteins, such as nitrogen fixation. In this review, we outline the mechanisms that the model diazotrophic bacterium Azotobacter vinelandii uses to ensure iron nutrition and how it adapts Fe metabolism to diazotrophic growth.