Sensation of electric fields in the Drosophila melanogaster larva

Electrosensation has emerged as a crucial sensory modality for social communication, foraging, and predation across the animal kingdom. However, its presence and functional role as well as the neural basis of electric field perception in Drosophila and other invertebrates remain unclear. In environm...

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Detalles Bibliográficos
Autores: Tadres, David, Riedl, Julia, 1981-, Eden, Alexander, Bontempo, Angela E., Lin, Jingtong, Reid, Samuel F., Roehrich, Brian, Williams, Kevin, Sepunaru, Lior, Louis, Matthieu
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/71093
Acceso en línea:http://hdl.handle.net/10230/71093
http://dx.doi.org/10.1016/j.cub.2025.03.014
Access Level:acceso abierto
Palabra clave:Drosophila larva
Gr33a
Gr66a
Electrosensation
Electrotaxis
Galvanotaxis
Gustatory neurons
Sensory navigation
Sensory neuroscience
Descripción
Sumario:Electrosensation has emerged as a crucial sensory modality for social communication, foraging, and predation across the animal kingdom. However, its presence and functional role as well as the neural basis of electric field perception in Drosophila and other invertebrates remain unclear. In environments with controlled electric fields, we identified electrosensation as a new sense in the Drosophila melanogaster larva. We found that the Drosophila larva performs robust electrotaxis: when exposed to a uniform electric field, larvae migrate toward the cathode (negatively charged elecrode) and quickly respond to changes in the orientation of the field to maintain cathodal movement. Through a behavioral screen, we identified a subset of sensory neurons located at the tip of the larval head that are necessary for electrotaxis. Calcium imaging revealed that a pair of Gr66a-positive sensory neurons (one on each side of the head) encodes the strength and orientation of the electric field. Our results indicate that electric fields elicit robust behavioral and neural responses in the Drosophila larva, providing new evidence for the significance of electrosensation in invertebrates.