Native quercetin as a chloride receptor in an organic solvent

The binding properties of quercetin toward chloride anions were investigated by means of1H-NMR, 13C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the bi...

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Detalles Bibliográficos
Autores: Abdi Bellau, M.L., Bortolini, O., Fantin, G., Fogagnolo, M., Ragno, D., Delso, I., Merino, P.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:76925
Acceso en línea:http://zaguan.unizar.es/record/76925
Access Level:acceso abierto
Descripción
Sumario:The binding properties of quercetin toward chloride anions were investigated by means of1H-NMR, 13C-NMR, and electrospray ionization mass spectrometry (ESI-MS) measurements, as well as computational calculations. The results indicate that quercetin behaves primarily as a ditopic receptor with the binding site of the B ring that exhibits stronger chloride affinity compared to the A ring. However, these sites are stronger receptors than those of catechol and resorcinol because of their conjugation with the carbonyl group located on the C ring. The 1:1 and 1:2 complexation of this flavonoid with Cl- was also supported by ESI mass spectrometry.