Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice

Metal ions are essential elements for all living organisms. However, metals can be toxic when present in excess. In plants, metal homeostasis is partly achieved through the function of metal transporters, including the diverse natural resistance-associated macrophage proteins (NRAMP). Among them, th...

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Autores: Peris Peris, Cristina, Serra Cardona, Albert, Sánchez Sanuy, Ferran, Campo Sánchez, Sonia|||0000-0001-5477-3162, Ariño, Joaquín, San Segundo de los Mozos, Blanca
Formato: artículo
Fecha de publicación:2017
País:España
Recursos:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/446967
Acesso em linha:https://hdl.handle.net/2117/446967
https://dx.doi.org/10.1094/MPMI-01-17-0005-R
Access Level:acceso abierto
Palavra-chave:Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Biotecnologia i millora genètica vegetal
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Indústries agroalimentàries::Indústria dels cereals i derivats
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Fitopatologia
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spelling Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in ricePeris Peris, CristinaSerra Cardona, AlbertSánchez Sanuy, FerranCampo Sánchez, Sonia|||0000-0001-5477-3162Ariño, JoaquínSan Segundo de los Mozos, BlancaÀrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Biotecnologia i millora genètica vegetalÀrees temàtiques de la UPC::Enginyeria agroalimentària::Indústries agroalimentàries::Indústria dels cereals i derivatsÀrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::FitopatologiaMetal ions are essential elements for all living organisms. However, metals can be toxic when present in excess. In plants, metal homeostasis is partly achieved through the function of metal transporters, including the diverse natural resistance-associated macrophage proteins (NRAMP). Among them, the OsNramp6 gene encodes a previously uncharacterized member of the rice NRAMP family that undergoes alternative splicing to produce different NRAMP6 proteins. In this work, we determined the metal transport activity and biological role of the full-length and the shortest NRAMP6 proteins (l-NRAMP6 and s-NRAMP6, respectively). Both l-NRAMP6 and s-NRAMP6 are plasma membrane-localized proteins that function as iron and manganese transporters. The expression of l-Nramp6 and s-Nramp6 is regulated during infection with the fungal pathogen Magnaporthe oryzae, albeit with different kinetics. Rice plants grown under high iron supply show stronger induction of rice defense genes and enhanced resistance to M. oryzae infection. Also, loss of function of OsNramp6 results in enhanced resistance to M. oryzae, supporting the idea that OsNramp6 negatively regulates rice immunity. Furthermore, nramp6 plants showed reduced biomass, pointing to a role of OsNramp6 in plant growth. A better understanding of OsNramp6-mediated mechanisms underlying disease resistance in rice will help in developing appropriate strategies for crop protection.20172017-05-0120252025-11-25journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/446967https://dx.doi.org/10.1094/MPMI-01-17-0005-Rreponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/4469672026-05-27T15:37:01Z
dc.title.none.fl_str_mv Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
title Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
spellingShingle Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
Peris Peris, Cristina
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Biotecnologia i millora genètica vegetal
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Indústries agroalimentàries::Indústria dels cereals i derivats
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Fitopatologia
title_short Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
title_full Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
title_fullStr Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
title_full_unstemmed Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
title_sort Two NRAMP6 isoforms function as iron and manganese transporters and contribute to disease resistance in rice
dc.creator.none.fl_str_mv Peris Peris, Cristina
Serra Cardona, Albert
Sánchez Sanuy, Ferran
Campo Sánchez, Sonia|||0000-0001-5477-3162
Ariño, Joaquín
San Segundo de los Mozos, Blanca
author Peris Peris, Cristina
author_facet Peris Peris, Cristina
Serra Cardona, Albert
Sánchez Sanuy, Ferran
Campo Sánchez, Sonia|||0000-0001-5477-3162
Ariño, Joaquín
San Segundo de los Mozos, Blanca
author_role author
author2 Serra Cardona, Albert
Sánchez Sanuy, Ferran
Campo Sánchez, Sonia|||0000-0001-5477-3162
Ariño, Joaquín
San Segundo de los Mozos, Blanca
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Biotecnologia i millora genètica vegetal
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Indústries agroalimentàries::Indústria dels cereals i derivats
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Fitopatologia
topic Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Biotecnologia i millora genètica vegetal
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Indústries agroalimentàries::Indústria dels cereals i derivats
Àrees temàtiques de la UPC::Enginyeria agroalimentària::Agricultura::Fitopatologia
description Metal ions are essential elements for all living organisms. However, metals can be toxic when present in excess. In plants, metal homeostasis is partly achieved through the function of metal transporters, including the diverse natural resistance-associated macrophage proteins (NRAMP). Among them, the OsNramp6 gene encodes a previously uncharacterized member of the rice NRAMP family that undergoes alternative splicing to produce different NRAMP6 proteins. In this work, we determined the metal transport activity and biological role of the full-length and the shortest NRAMP6 proteins (l-NRAMP6 and s-NRAMP6, respectively). Both l-NRAMP6 and s-NRAMP6 are plasma membrane-localized proteins that function as iron and manganese transporters. The expression of l-Nramp6 and s-Nramp6 is regulated during infection with the fungal pathogen Magnaporthe oryzae, albeit with different kinetics. Rice plants grown under high iron supply show stronger induction of rice defense genes and enhanced resistance to M. oryzae infection. Also, loss of function of OsNramp6 results in enhanced resistance to M. oryzae, supporting the idea that OsNramp6 negatively regulates rice immunity. Furthermore, nramp6 plants showed reduced biomass, pointing to a role of OsNramp6 in plant growth. A better understanding of OsNramp6-mediated mechanisms underlying disease resistance in rice will help in developing appropriate strategies for crop protection.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-05-01
2025
2025-11-25
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/446967
https://dx.doi.org/10.1094/MPMI-01-17-0005-R
url https://hdl.handle.net/2117/446967
https://dx.doi.org/10.1094/MPMI-01-17-0005-R
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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