Interaction between Geminivirus Replication Protein and the SUMO-Conjugating Enzyme Is Required for Viral Infection

Geminiviruses are small DNA viruses that replicate in nuclei of infected plant cells by using plant DNA polymerases. These viruses encode a protein designated AL1, Rep, or AC1 that is essential for viral replication. AL1 is an oligomeric protein that binds to double-stranded DNA, catalyzes the cleav...

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Detalhes bibliográficos
Autores: Sánchez-Durán, Miguel A., Dallas, Mary B., Ascencio-Ibañez, José T., Reyes, María Inés, Arroyo-Mateos, Manuel, Ruiz-Albert, Javier, Hanley-Bowdoin, Linda, Bejarano, Eduardo R.
Formato: artículo
Fecha de publicación:2011
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/40006
Acesso em linha:http://hdl.handle.net/10261/40006
Access Level:acceso abierto
Palavra-chave:Geminivurs
Viral Infection
Descrição
Resumo:Geminiviruses are small DNA viruses that replicate in nuclei of infected plant cells by using plant DNA polymerases. These viruses encode a protein designated AL1, Rep, or AC1 that is essential for viral replication. AL1 is an oligomeric protein that binds to double-stranded DNA, catalyzes the cleavage and ligation of single-stranded DNA, and induces the accumulation of host replication machinery.

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