Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells

[Background] Transglycosylation represents one of the most promising approaches for obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the best targets for creating new molecules with enhanced capacities. These compounds can be found in diet and exhibit a wide range...

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Detalles Bibliográficos
Autores: Méndez-Líter, Juan A., Tundidor, Isabel, Nieto-Domínguez, Manuel José, Fernández de Toro, Beatriz, Santana, Andrés G., Eugenio, Laura I. de, Prieto Orzanco, Alicia, Asensio, Juan Luis, Cañada, F. Javier, Sánchez, Cristina, Martínez, María Jesús
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/183085
Acceso en línea:http://hdl.handle.net/10261/183085
Access Level:acceso abierto
Palabra clave:Transglycosylation
β-Glucosidases
Glycosyl hydrolases
Hydroxytyrosol
Vanillin
Glucosides
Breast cancer cells
Descripción
Sumario:[Background] Transglycosylation represents one of the most promising approaches for obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the best targets for creating new molecules with enhanced capacities. These compounds can be found in diet and exhibit a wide range of bioactivities, such as antioxidant, antihypertensive, antitumor, neuroprotective and anti-inflammatory, and the eco-friendly synthesis of glycosides from these molecules can be a suitable alternative for increasing their health benefits.