Detections of rare enterovirus C105 linked to an emerging novel clade, Spain, 2019 to 2024
Enterovirus (EV)-C105 is a rare genotype not previously detected in Spain. Between 2019 and 2024, we detected EV-C105 in respiratory samples of five patients, through routine EV surveillance. Three cases had respiratory illness and two were hospitalised for neurological illness. Four of the five seq...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Instituto de Salud Carlos III (ISCIII) |
| Repositorio: | Repisalud |
| Idioma: | inglés |
| OAI Identifier: | oai:repisalud.isciii.es:20.500.12105/26533 |
| Acceso en línea: | https://hdl.handle.net/20.500.12105/26533 |
| Access Level: | acceso abierto |
| Palabra clave: | Enterovirus C Acute flaccid paralysis Molecular surveillance Adult Child Child, Preschool Enterovirus Enterovirus C, Human Enterovirus Infections Female Genotype Humans Male Middle Aged Phylogeny RNA, Viral Respiratory Tract Infections Spain |
| Sumario: | Enterovirus (EV)-C105 is a rare genotype not previously detected in Spain. Between 2019 and 2024, we detected EV-C105 in respiratory samples of five patients, through routine EV surveillance. Three cases had respiratory illness and two were hospitalised for neurological illness. Four of the five sequenced strains belonged to an emerging clade (C1), defined by four novel nonsynonymous mutations in key antigenic epitopes. We recommend reinforced clinical awareness and EV genomic surveillance, including respiratory samples, even when symptoms are neurological. |
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