New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis

A collective view of the degradation of monochlorocatechols in fungi is yet to be attained, though these compounds are recognised as key degradation intermediates of numerous chlorinated aromatic hydrocarbons, including monochlorophenols. In the present contribution we have analysed the degradation...

Descripción completa

Detalles Bibliográficos
Autores: Martins, Tiago M., Núñez Burcio, Oscar, Gallart Ayala, Hèctor, Leitao, M. Cristina, Galcerán Huguet, M. Teresa, Pereira, Cristina Silvia
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2014
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/99011
Acceso en línea:https://hdl.handle.net/2445/99011
Access Level:acceso abierto
Palabra clave:Biodegradació
Fongs
Biodegradation
Fungi
id ES_f97cf43d9ca80d1c7f58afcd562ff0f6
oai_identifier_str oai:diposit.ub.edu:2445/99011
network_acronym_str ES
network_name_str España
repository_id_str
spelling New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysisMartins, Tiago M.Núñez Burcio, OscarGallart Ayala, HèctorLeitao, M. CristinaGalcerán Huguet, M. TeresaPereira, Cristina SilviaBiodegradacióFongsBiodegradationFungiA collective view of the degradation of monochlorocatechols in fungi is yet to be attained, though these compounds are recognised as key degradation intermediates of numerous chlorinated aromatic hydrocarbons, including monochlorophenols. In the present contribution we have analysed the degradation pathways of monochlorophenols in Aspergillus nidulans using essentially metabolomics. Degradation intermediates herein identified included those commonly reported (e.g. 3-chloro-cis,cis-muconate) but also compounds never reported before in fungi revealing for 4-chlorocatechol and for 3- chlorocatechol unknown degradation paths yielding 3-chlorodienelactone and catechol, respectively. A different 3-chlorocatechol degradation path led to accumulation of 2- chloromuconates (a potential dead-end), notwithstanding preliminary evidence of chloromuconolactones and protoanemonin simultaneous formation. In addition, some transformation intermediates, of which sulfate conjugates of monochlorophenols/ chlorocatechols were the most common, were also identified. This study provides critical information for understanding the role of fungi in the degradation of chlorinated aromatic hydrocarbons; furthering their utility in the development of innovative bioremediation strategies.Elsevier B.V.2014info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://hdl.handle.net/2445/99011Articles publicats en revistes (Enginyeria Química i Química Analítica)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésVersió postprint del document publicat a: http://dx.doi.org/10.1016/j.jhazmat.2014.01.024Journal of Hazardous Materials, 2014, vol. 268, p. 264-272http://dx.doi.org/10.1016/j.jhazmat.2014.01.024(c) Elsevier B.V., 2014info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/990112026-05-27T06:46:51Z
dc.title.none.fl_str_mv New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
title New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
spellingShingle New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
Martins, Tiago M.
Biodegradació
Fongs
Biodegradation
Fungi
title_short New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
title_full New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
title_fullStr New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
title_full_unstemmed New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
title_sort New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis
dc.creator.none.fl_str_mv Martins, Tiago M.
Núñez Burcio, Oscar
Gallart Ayala, Hèctor
Leitao, M. Cristina
Galcerán Huguet, M. Teresa
Pereira, Cristina Silvia
author Martins, Tiago M.
author_facet Martins, Tiago M.
Núñez Burcio, Oscar
Gallart Ayala, Hèctor
Leitao, M. Cristina
Galcerán Huguet, M. Teresa
Pereira, Cristina Silvia
author_role author
author2 Núñez Burcio, Oscar
Gallart Ayala, Hèctor
Leitao, M. Cristina
Galcerán Huguet, M. Teresa
Pereira, Cristina Silvia
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Biodegradació
Fongs
Biodegradation
Fungi
topic Biodegradació
Fongs
Biodegradation
Fungi
description A collective view of the degradation of monochlorocatechols in fungi is yet to be attained, though these compounds are recognised as key degradation intermediates of numerous chlorinated aromatic hydrocarbons, including monochlorophenols. In the present contribution we have analysed the degradation pathways of monochlorophenols in Aspergillus nidulans using essentially metabolomics. Degradation intermediates herein identified included those commonly reported (e.g. 3-chloro-cis,cis-muconate) but also compounds never reported before in fungi revealing for 4-chlorocatechol and for 3- chlorocatechol unknown degradation paths yielding 3-chlorodienelactone and catechol, respectively. A different 3-chlorocatechol degradation path led to accumulation of 2- chloromuconates (a potential dead-end), notwithstanding preliminary evidence of chloromuconolactones and protoanemonin simultaneous formation. In addition, some transformation intermediates, of which sulfate conjugates of monochlorophenols/ chlorocatechols were the most common, were also identified. This study provides critical information for understanding the role of fungi in the degradation of chlorinated aromatic hydrocarbons; furthering their utility in the development of innovative bioremediation strategies.
publishDate 2014
dc.date.none.fl_str_mv 2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/99011
url https://hdl.handle.net/2445/99011
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.jhazmat.2014.01.024
Journal of Hazardous Materials, 2014, vol. 268, p. 264-272
http://dx.doi.org/10.1016/j.jhazmat.2014.01.024
dc.rights.none.fl_str_mv (c) Elsevier B.V., 2014
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Elsevier B.V., 2014
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Enginyeria Química i Química Analítica)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869425099517460480
score 15.300719

Similares en LA Referencia