Diagnosis and treatment of renal ANCA vasculitis: a summary of the consensus document of the Catalan Group for the Study of Glomerular Diseases (GLOMCAT)

The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, c...

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Bibliographic Details
Authors: Bordignon Draibe, Juliana, Marco, Helena, Ibernón, Meritxell, Agraz, Irene, Arcal, Carola, Barros Freiría, Xoana, Cabrera, Victoria, Da Silva, Iara, Diaz Encarnación, Montserrat, Fulladosa, Xavier, Guillén, Elena, Lescano, Patricia, Martinez Valenzuela, Laura, Márquez, Eva, Martín, Nadia, Merino Ribas, Ana, Navarro, Maru, Rodríguez, Eva, Soler, María José, Torras Ambròs, Joan, Quintana Porras, Luis F.
Format: article
Status:Published version
Publication Date:2024
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/220148
Online Access:https://hdl.handle.net/2445/220148
Access Level:Open access
Keyword:Inflamació
Vasculitis
Malalties autoimmunitàries
Inflammation
Autoimmune diseases
Description
Summary:The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, clinical presentation, histopathological classification, monitoring strategies, induction and maintenance treatments, as well as special considerations for relapsing, refractory, and frail patients with renal AAV. The document was prepared by the Catalan Group for the Study of Glomerular Diseases (GLOMCAT), which comprises nephrologists with extensive experience in the diagnosis and treatment of AAV patients. Several virtual and face-to-face meetings were held for coordination, section assignments, and content discussion. An exhaustive and systematic search of the literature was carried out, which included, among others, the following databases: PubMed, EMBASE, Cochrane Library, Google Scholar, and ClinicalTrials.gov, as well as the abstract books of national and international congresses. Overall, the document provides a comprehensive guide for clinicians managing patients with renal AAV, offering evidence-based recommendations for diagnosis, monitoring, and treatment across various clinical scenarios.

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