Masupirdine, a Selective Serotonin 5-HT6 Receptor Antagonist for Alzheimer’s Disease
Masupirdine is an oral, small, and safe molecule, readily available by a robust, twostep synthetic scheme, showing a potent, selective serotonin 5-HT 6 receptor antagonist profile, procognitive effects in various behavioral animal models in Phase 3 clinical trials for the treatment of agitation in p...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2026 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/421566 |
| Acceso en línea: | http://hdl.handle.net/10261/421566 |
| Access Level: | acceso abierto |
| Palabra clave: | Alzheimer’s disease 5-HT T 6 R antagonist Masupirdine |
| Sumario: | Masupirdine is an oral, small, and safe molecule, readily available by a robust, twostep synthetic scheme, showing a potent, selective serotonin 5-HT 6 receptor antagonist profile, procognitive effects in various behavioral animal models in Phase 3 clinical trials for the treatment of agitation in patients with Alzheimer’s dementia. |
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