A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information

INGA FOOD, S.A. initiated a crossbreeding program involving two Iberian pig varieties: Retinto and Entrepelado. The primary objective of this program is to produce an F1 hybrid sow that exhibits enhanced reproductive performance. In a previous investigation, variations in the reproductive performanc...

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Autores: Srihi, Houssemeddine|||0000-0002-9249-3070, López Carbonell, David|||0000-0003-0964-9212, Ibañez-Escriche, Noelia|||0000-0002-6221-3576, Casellas Vidal, Joaquim|||0000-0002-4982-3556, Hernández Penadés, Pilar|||0000-0001-7857-7334, Negro, Sara, Varona, Luis|||0000-0001-6256-5478
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:275887
Acceso en línea:https://ddd.uab.cat/record/275887
https://dx.doi.org/urn:doi:10.3390/ani13101648
Access Level:acceso abierto
Palabra clave:Gametic model
Iberian pig
Crossbreeding
Retinto
Entrepelado
id ES_f867ebd976ebddd9ba80b196607bea56
oai_identifier_str oai:ddd.uab.cat:275887
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
An Example with Two Iberian Varieties
title A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
spellingShingle A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
Srihi, Houssemeddine|||0000-0002-9249-3070
Gametic model
Iberian pig
Crossbreeding
Retinto
Entrepelado
title_short A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
title_full A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
title_fullStr A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
title_full_unstemmed A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
title_sort A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic Information
dc.creator.none.fl_str_mv Srihi, Houssemeddine|||0000-0002-9249-3070
López Carbonell, David|||0000-0003-0964-9212
Ibañez-Escriche, Noelia|||0000-0002-6221-3576
Casellas Vidal, Joaquim|||0000-0002-4982-3556
Hernández Penadés, Pilar|||0000-0001-7857-7334
Negro, Sara
Varona, Luis|||0000-0001-6256-5478
author Srihi, Houssemeddine|||0000-0002-9249-3070
author_facet Srihi, Houssemeddine|||0000-0002-9249-3070
López Carbonell, David|||0000-0003-0964-9212
Ibañez-Escriche, Noelia|||0000-0002-6221-3576
Casellas Vidal, Joaquim|||0000-0002-4982-3556
Hernández Penadés, Pilar|||0000-0001-7857-7334
Negro, Sara
Varona, Luis|||0000-0001-6256-5478
author_role author
author2 López Carbonell, David|||0000-0003-0964-9212
Ibañez-Escriche, Noelia|||0000-0002-6221-3576
Casellas Vidal, Joaquim|||0000-0002-4982-3556
Hernández Penadés, Pilar|||0000-0001-7857-7334
Negro, Sara
Varona, Luis|||0000-0001-6256-5478
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Gametic model
Iberian pig
Crossbreeding
Retinto
Entrepelado
topic Gametic model
Iberian pig
Crossbreeding
Retinto
Entrepelado
description INGA FOOD, S.A. initiated a crossbreeding program involving two Iberian pig varieties: Retinto and Entrepelado. The primary objective of this program is to produce an F1 hybrid sow that exhibits enhanced reproductive performance. In a previous investigation, variations in the reproductive performance of sows, specifically litter size, were observed among the reciprocal crosses. These variations indicate the presence of genomic imprinting effects. To assess the influence of genetic origin, we developed a multivariate gametic model to estimate the gametic correlations between paternal and maternal effects. Gametic correlations lower than one could potentially explain the performance differences observed across the reciprocal crosses. Despite having limited data, the study's findings suggest that the gametic correlation estimate between paternal and maternal effects on litter size is lower in the Entrepelado population compared to the Retinto population. INGA FOOD, S.A. initiated a crossbreeding program between two Iberian pig varieties, Retinto (R) and Entrepelado (E), with the goal of producing a hybrid sow (F1). Several studies have been conducted to evaluate its productive performance, and these studies have revealed differences in litter size between the two reciprocal crosses, suggesting the presence of genomic imprinting effects. To further investigate these effects, this study introduces a multivariate gametic model designed to estimate gametic correlations between paternal and maternal effects originating from both genetic backgrounds involved in the reciprocal crosses. The dataset consisted of 1258 records (the total number born-TNB and the number born alive-NBA) from 203 crossbred dams for the Entrepelado (sire) × Retinto (dam) cross and 700 records from 125 crossbred dams for the Retinto (sire) × Entrepelado (dam) cross. All animals were genotyped using the GeneSeek ® GPP Porcine 70 K HDchip (Illumina Inc., San Diego, CA, USA). The results indicated that the posterior distribution of the gametic correlation between paternal and maternal effects was distinctly different between the two populations. Specifically, in the Retinto population, the gametic correlation showed a positive skew with posterior probabilities of 0.78 for the TNB and 0.80 for the NBA. On the other hand, the Entrepelado population showed a posterior probability of a positive gametic correlation between paternal and maternal effects of approximately 0.50. The differences in the shape of the posterior distribution of the gametic correlations between paternal and maternal effects observed in the two varieties may account for the distinct performance outcomes observed in the reciprocal crosses.
publishDate 2023
dc.date.none.fl_str_mv 2
2023-01-01
2023
2023-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/275887
https://dx.doi.org/urn:doi:10.3390/ani13101648
url https://ddd.uab.cat/record/275887
https://dx.doi.org/urn:doi:10.3390/ani13101648
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Agencia Estatal de Investigación https://doi.org/10.13039/501100011033 CGL2016-80155-R
Agencia Estatal de Investigación https://doi.org/10.13039/501100011033 PID2020-114705RB-I00
European Commission https://doi.org/10.13039/501100000780 801586
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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spelling A Bayesian Multivariate Gametic Model in a Reciprocal Cross with Genomic InformationAn Example with Two Iberian VarietiesSrihi, Houssemeddine|||0000-0002-9249-3070López Carbonell, David|||0000-0003-0964-9212Ibañez-Escriche, Noelia|||0000-0002-6221-3576Casellas Vidal, Joaquim|||0000-0002-4982-3556Hernández Penadés, Pilar|||0000-0001-7857-7334Negro, SaraVarona, Luis|||0000-0001-6256-5478Gametic modelIberian pigCrossbreedingRetintoEntrepeladoINGA FOOD, S.A. initiated a crossbreeding program involving two Iberian pig varieties: Retinto and Entrepelado. The primary objective of this program is to produce an F1 hybrid sow that exhibits enhanced reproductive performance. In a previous investigation, variations in the reproductive performance of sows, specifically litter size, were observed among the reciprocal crosses. These variations indicate the presence of genomic imprinting effects. To assess the influence of genetic origin, we developed a multivariate gametic model to estimate the gametic correlations between paternal and maternal effects. Gametic correlations lower than one could potentially explain the performance differences observed across the reciprocal crosses. Despite having limited data, the study's findings suggest that the gametic correlation estimate between paternal and maternal effects on litter size is lower in the Entrepelado population compared to the Retinto population. INGA FOOD, S.A. initiated a crossbreeding program between two Iberian pig varieties, Retinto (R) and Entrepelado (E), with the goal of producing a hybrid sow (F1). Several studies have been conducted to evaluate its productive performance, and these studies have revealed differences in litter size between the two reciprocal crosses, suggesting the presence of genomic imprinting effects. To further investigate these effects, this study introduces a multivariate gametic model designed to estimate gametic correlations between paternal and maternal effects originating from both genetic backgrounds involved in the reciprocal crosses. The dataset consisted of 1258 records (the total number born-TNB and the number born alive-NBA) from 203 crossbred dams for the Entrepelado (sire) × Retinto (dam) cross and 700 records from 125 crossbred dams for the Retinto (sire) × Entrepelado (dam) cross. All animals were genotyped using the GeneSeek ® GPP Porcine 70 K HDchip (Illumina Inc., San Diego, CA, USA). The results indicated that the posterior distribution of the gametic correlation between paternal and maternal effects was distinctly different between the two populations. Specifically, in the Retinto population, the gametic correlation showed a positive skew with posterior probabilities of 0.78 for the TNB and 0.80 for the NBA. On the other hand, the Entrepelado population showed a posterior probability of a positive gametic correlation between paternal and maternal effects of approximately 0.50. The differences in the shape of the posterior distribution of the gametic correlations between paternal and maternal effects observed in the two varieties may account for the distinct performance outcomes observed in the reciprocal crosses. 22023-01-0120232023-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/275887https://dx.doi.org/urn:doi:10.3390/ani13101648reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengAgencia Estatal de Investigación https://doi.org/10.13039/501100011033 CGL2016-80155-RAgencia Estatal de Investigación https://doi.org/10.13039/501100011033 PID2020-114705RB-I00European Commission https://doi.org/10.13039/501100000780 801586open accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2758872026-06-06T12:50:31Z
score 15.301603

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