New Insights in Therapy for Food Allergy

Food allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many effo...

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Detalhes bibliográficos
Autores: Mayorga, Cristobalina, Palomares, Francisca, Cañas, José A., Pérez-Sánchez, Natalia, Núñez, Rafael, Torres, María José, Gómez, Francisca
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:España
Recursos:Universidad de Sevilla (US)
Repositório:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/154036
Acesso em linha:https://hdl.handle.net/11441/154036
https://doi.org/10.3390/foods10051037
Access Level:Acceso aberto
Palavra-chave:food allergy
specific immunotherapy
non-specific therapy
hypoallergens
nanoparticles
microbiota
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spelling New Insights in Therapy for Food AllergyMayorga, CristobalinaPalomares, FranciscaCañas, José A.Pérez-Sánchez, NataliaNúñez, RafaelTorres, María JoséGómez, Franciscafood allergyspecific immunotherapynon-specific therapyhypoallergensnanoparticlesmicrobiotaFood allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many efforts have been made to better understand the humoral and cellular mechanisms involved in food allergy and to improve the strategies for diagnosis and treatment. This review illustrates IgE-mediated food hypersensitivity and provides a current description of the diagnostic strategies and advances in different treatments. Specific immunotherapy, including different routes of administration and new therapeutic approaches, such as hypoallergens and nanoparticles, are discussed in detail. Other treatments, such as biologics and microbiota, are also described. Therefore, we conclude that although important efforts have been made in improving therapies for food allergies, including innovative approaches mainly focusing on efficacy and safety, there is an urgent need to develop a set of basic and clinical results to help in the diagnosis and treatment of food allergies.MDPIBioquímica Médica y Biología Molecular e Inmunología2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/154036https://doi.org/10.3390/foods10051037reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)Ingléshttps://www.mdpi.com/2304-8158/10/5/1037info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1540362026-06-17T12:51:07Z
dc.title.none.fl_str_mv New Insights in Therapy for Food Allergy
title New Insights in Therapy for Food Allergy
spellingShingle New Insights in Therapy for Food Allergy
Mayorga, Cristobalina
food allergy
specific immunotherapy
non-specific therapy
hypoallergens
nanoparticles
microbiota
title_short New Insights in Therapy for Food Allergy
title_full New Insights in Therapy for Food Allergy
title_fullStr New Insights in Therapy for Food Allergy
title_full_unstemmed New Insights in Therapy for Food Allergy
title_sort New Insights in Therapy for Food Allergy
dc.creator.none.fl_str_mv Mayorga, Cristobalina
Palomares, Francisca
Cañas, José A.
Pérez-Sánchez, Natalia
Núñez, Rafael
Torres, María José
Gómez, Francisca
author Mayorga, Cristobalina
author_facet Mayorga, Cristobalina
Palomares, Francisca
Cañas, José A.
Pérez-Sánchez, Natalia
Núñez, Rafael
Torres, María José
Gómez, Francisca
author_role author
author2 Palomares, Francisca
Cañas, José A.
Pérez-Sánchez, Natalia
Núñez, Rafael
Torres, María José
Gómez, Francisca
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Bioquímica Médica y Biología Molecular e Inmunología
dc.subject.none.fl_str_mv food allergy
specific immunotherapy
non-specific therapy
hypoallergens
nanoparticles
microbiota
topic food allergy
specific immunotherapy
non-specific therapy
hypoallergens
nanoparticles
microbiota
description Food allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many efforts have been made to better understand the humoral and cellular mechanisms involved in food allergy and to improve the strategies for diagnosis and treatment. This review illustrates IgE-mediated food hypersensitivity and provides a current description of the diagnostic strategies and advances in different treatments. Specific immunotherapy, including different routes of administration and new therapeutic approaches, such as hypoallergens and nanoparticles, are discussed in detail. Other treatments, such as biologics and microbiota, are also described. Therefore, we conclude that although important efforts have been made in improving therapies for food allergies, including innovative approaches mainly focusing on efficacy and safety, there is an urgent need to develop a set of basic and clinical results to help in the diagnosis and treatment of food allergies.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/154036
https://doi.org/10.3390/foods10051037
url https://hdl.handle.net/11441/154036
https://doi.org/10.3390/foods10051037
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.mdpi.com/2304-8158/10/5/1037
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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