The minimal chemotactic cell

The movement of cells and microorganisms in response to chemical gradients (chemotaxis) has played an essential role in the evolution of many biological processes. Cellular navigation works via the holistic assembly of numerous components into machineries that transform chemical energy into locomoti...

Descripción completa

Detalles Bibliográficos
Autores: Battaglia, Giuseppe, Borges Fernandes, Barbara, Apriceno, Azzurra, Arango-Restrepo, Andrés, Almadhi, Safa, Ghosh, Subhadip, Forth, Joe, López-Alonso, Jorge Pedro, Ubarretxena-Belandia, Iban, Rubi, José Miguel, Ruiz-Perez, Lorena, Williams, Ian
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/224519
Acceso en línea:https://hdl.handle.net/2445/224519
Access Level:acceso abierto
Palabra clave:Cèl·lules
Glucosa
Quimiotaxi
Cells
Glucose
Chemotaxis
Descripción
Sumario:The movement of cells and microorganisms in response to chemical gradients (chemotaxis) has played an essential role in the evolution of many biological processes. Cellular navigation works via the holistic assembly of numerous components into machineries that transform chemical energy into locomotion. Herein we present and discuss the minimal elements required for cell-like vesicles to be chemotactic. We show that lipid vesicles can propel themselves in response to chemical gradients when only a transmembrane protein and an encapsulated enzyme are incorporated into the vesicle structure. The herein proposed model serves as a proof of concept to show that even the simplest cell-like structure can experience chemotactic navigation.