Ancient evolutionary signals of protein-coding sequences allow the discovery of new genes in the Drosophila melanogaster genome

[Background]: The current growth in DNA sequencing techniques makes of genome annotation a crucial task in the genomic era. Traditional gene finders focus on protein-coding sequences, but they are far from being exhaustive. The number of this kind of genes continuously increases due to new experimen...

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Detalhes bibliográficos
Autores: Casimiro-Soriguer, Carlos S., Rubio, Alejandro, Jiménez-Martínez, Juan, Pérez-Pulido, Antonio J.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/222425
Acesso em linha:http://hdl.handle.net/10261/222425
Access Level:acceso abierto
Palavra-chave:Ancient sequences
Gene finding
Protein-coding genes
Drosophila melanogaster
Descrição
Resumo:[Background]: The current growth in DNA sequencing techniques makes of genome annotation a crucial task in the genomic era. Traditional gene finders focus on protein-coding sequences, but they are far from being exhaustive. The number of this kind of genes continuously increases due to new experimental data and development of improved bioinformatics algorithms.