Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge

The release of pharmaceutically active compounds to the soils through the application of sewage sludge and the irrigation with wastewater, or even with surface water, is constant. The adsorption of these compounds onto the soil is one of the key factors affecting their fate in the environment and th...

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Detalhes bibliográficos
Autores: Malvar Guzmán, José Luis, Santos Morcillo, Juan Luis, Martín Bueno, Julia, Aparicio Gómez, Irene, Alonso Álvarez, Esteban
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/126670
Acesso em linha:https://hdl.handle.net/11441/126670
https://doi.org/10.3390/molecules25225306
Access Level:acceso abierto
Palavra-chave:Carbamazepine
Competitive adsorption
Metabolites
Sewage sludge
Soil
Wastewater
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spelling Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage SludgeMalvar Guzmán, José LuisSantos Morcillo, Juan LuisMartín Bueno, JuliaAparicio Gómez, IreneAlonso Álvarez, EstebanCarbamazepineCompetitive adsorptionMetabolitesSewage sludgeSoilWastewaterThe release of pharmaceutically active compounds to the soils through the application of sewage sludge and the irrigation with wastewater, or even with surface water, is constant. The adsorption of these compounds onto the soil is one of the key factors affecting their fate in the environment and their potential environmental risks. In this work, the adsorption of carbamazepine (CBZ) and its metabolites, 3-hydroxy-carbamazepine (3OH-CBZ), carbamazepine-10,11-dihydro-10,11-epoxide (EP-CBZ), and 10,11-dihydro-10-hydroxycarbamazepine (10OH-CBZ), in three Mediterranean soils was evaluated using single-solute and four-solute experiments. The highest adsorptions were measured for 3OH-CBZ, followed by CBZ, EP-CBZ, and 10OH-CBZ, in that order. A high influence of the physicochemical characteristics of the compounds, pH, and soil characteristics in the adsorption of the studied compounds was observed and corroborated by the statistical analysis of the results. Moreover, a good fit was observed in the three isotherm models evaluated (linear, Freundlich, and Langmuir) in single-solute experiments (R2 > 0.90). However, a decrease of the measured adsorptions and a worse fit to the isotherm models were observed in the case of multiple-solute experiments. This could be mainly due to the competition established between the studied compounds for the active sites of the soils.Ministerio de Economía y Competitividad CTM2017-82778-RMultidisciplinary Digital Publishing Institute (MDPI)Química Analítica2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/126670https://doi.org/10.3390/molecules25225306reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésMolecules, 25 (22), 5306.CTM2017-82778-Rhttps://doi.org/10.3390/molecules25225306info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1266702026-06-17T12:51:07Z
dc.title.none.fl_str_mv Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
title Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
spellingShingle Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
Malvar Guzmán, José Luis
Carbamazepine
Competitive adsorption
Metabolites
Sewage sludge
Soil
Wastewater
title_short Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
title_full Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
title_fullStr Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
title_full_unstemmed Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
title_sort Approach to the Dynamic of Carbamazepine and its Main Metabolites in Soil Contamination through the Reuse of Wastewater and Sewage Sludge
dc.creator.none.fl_str_mv Malvar Guzmán, José Luis
Santos Morcillo, Juan Luis
Martín Bueno, Julia
Aparicio Gómez, Irene
Alonso Álvarez, Esteban
author Malvar Guzmán, José Luis
author_facet Malvar Guzmán, José Luis
Santos Morcillo, Juan Luis
Martín Bueno, Julia
Aparicio Gómez, Irene
Alonso Álvarez, Esteban
author_role author
author2 Santos Morcillo, Juan Luis
Martín Bueno, Julia
Aparicio Gómez, Irene
Alonso Álvarez, Esteban
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Química Analítica
dc.subject.none.fl_str_mv Carbamazepine
Competitive adsorption
Metabolites
Sewage sludge
Soil
Wastewater
topic Carbamazepine
Competitive adsorption
Metabolites
Sewage sludge
Soil
Wastewater
description The release of pharmaceutically active compounds to the soils through the application of sewage sludge and the irrigation with wastewater, or even with surface water, is constant. The adsorption of these compounds onto the soil is one of the key factors affecting their fate in the environment and their potential environmental risks. In this work, the adsorption of carbamazepine (CBZ) and its metabolites, 3-hydroxy-carbamazepine (3OH-CBZ), carbamazepine-10,11-dihydro-10,11-epoxide (EP-CBZ), and 10,11-dihydro-10-hydroxycarbamazepine (10OH-CBZ), in three Mediterranean soils was evaluated using single-solute and four-solute experiments. The highest adsorptions were measured for 3OH-CBZ, followed by CBZ, EP-CBZ, and 10OH-CBZ, in that order. A high influence of the physicochemical characteristics of the compounds, pH, and soil characteristics in the adsorption of the studied compounds was observed and corroborated by the statistical analysis of the results. Moreover, a good fit was observed in the three isotherm models evaluated (linear, Freundlich, and Langmuir) in single-solute experiments (R2 > 0.90). However, a decrease of the measured adsorptions and a worse fit to the isotherm models were observed in the case of multiple-solute experiments. This could be mainly due to the competition established between the studied compounds for the active sites of the soils.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/126670
https://doi.org/10.3390/molecules25225306
url https://hdl.handle.net/11441/126670
https://doi.org/10.3390/molecules25225306
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Molecules, 25 (22), 5306.
CTM2017-82778-R
https://doi.org/10.3390/molecules25225306
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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