Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.

OBJECTIVES: To identify predictors of malaria and arboviral disease in patients with febrile syndrome who seek care after traveling from tropical or subtropical locations. MATERIAL AND METHODS: Observational retrospective cohort study. We collected demographic, epidemiologic, and clinical data; labo...

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Autores: López-Amorós AI, Torrús-Tendero D, Merino De Lucas E, Reus Bañuls S, Boix Martínez V, Llorens Soriano P, Escribano Cañadas I, Ramos-Rincón JM
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
Repositorio:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
OAI Identifier:oai:isabial.fundanetsuite.com:p9589
Acesso em linha:https://isabial.portalinvestigacion.com/publicaciones9589
http://emergencias.portalsemes.org/descargar/factores-asociados-con-malaria-y-arboviriasis-en-pacientes-con-sndrome-febril-importado-estudio-de-cohortes-retrospectivo/
Access Level:acceso abierto
Palavra-chave:Arboviral diseases.
Arboviriasis.
Dengue.
Enfermedades relacionadas con el viaje.
Fever.
Fiebre.
Malaria.
Medicina del viajero.
Travel medicine.
Travel-related disease.
Travel.
Viajero.
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spelling Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.López-Amorós AITorrús-Tendero DMerino De Lucas EReus Bañuls SBoix Martínez VLlorens Soriano PEscribano Cañadas IRamos-Rincón JMArboviral diseases.Arboviriasis.Dengue.Enfermedades relacionadas con el viaje.Fever.Fiebre.Malaria.Medicina del viajero.Travel medicine.Travel-related disease.Travel.Viajero.OBJECTIVES: To identify predictors of malaria and arboviral disease in patients with febrile syndrome who seek care after traveling from tropical or subtropical locations. MATERIAL AND METHODS: Observational retrospective cohort study. We collected demographic, epidemiologic, and clinical data; laboratory findings; and the clinical and final microbiologic diagnoses. Multivariate analysis was used to calculate indices of diagnostic accuracy (sensitivity, specificity, and predictive values) and coefficients of probability of combinations of variables. RESULTS: Data for 291 patients with febrile syndrome were included; 108 had malaria (37.1%), 28 had an arboviral disease (9.6%), and 155 had other causes of fever (53.3%). Multivariate analysis showed patients most likely to have malaria were those from sub-Saharan Africa, adjusted odds ratio (aOR) of 45.85 (95% CI, 9.45-222.49); immigrants who returned to visit friends and relatives (VFR), aOR of 3.55 (95% CI, 1.21-10.46); or had platelet concentrations 150 000/mm3, aORa of 16.47 (95% CI, 5.46-49.70) or headache, aOR of 10.62 (95% CI, 3.20-35.28). The combination of these 4 variables gave a positive probability coefficient (PPC) of 23.72 (95% CI, 5.76-97.62). Patients with febrile syndrome most likely to have an arboviral disease were those from Central or South America, OR 5.07 (95% CI, 1.73-14.92), and those who had exanthems, OR 5.10 (95% CI, 1.72-17.02) or joint pain, OR 14.50 (95% CI, 3.05-68.80). The combination of these 3 variables gave a PPC of 20.66 (95% CI, 7.74-55.21). CONCLUSION: Patients with febrile syndrome with the greatest probability of having malaria are those from sub-Saharan Africa, those who are VFR, and those with platelet concentrations under 150.000/µL or headache. Arboviral disease was more likely in patients from Central and South America who had exanthems or joint pain.Soc Espanola Medicina Urgencias & Emergencias-SEMES2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://isabial.portalinvestigacion.com/publicaciones9589http://emergencias.portalsemes.org/descargar/factores-asociados-con-malaria-y-arboviriasis-en-pacientes-con-sndrome-febril-importado-estudio-de-cohortes-retrospectivo/EmergenciasISSN: 11376821ISSNe: 23865857reponame:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicanteinstname:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)Españolinfo:eu-repo/semantics/openAccessoai:isabial.fundanetsuite.com:p95892026-06-12T10:20:37Z
dc.title.none.fl_str_mv Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
title Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
spellingShingle Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
López-Amorós AI
Arboviral diseases.
Arboviriasis.
Dengue.
Enfermedades relacionadas con el viaje.
Fever.
Fiebre.
Malaria.
Medicina del viajero.
Travel medicine.
Travel-related disease.
Travel.
Viajero.
title_short Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
title_full Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
title_fullStr Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
title_full_unstemmed Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
title_sort Factores asociados con malaria y arboviriasis en pacientes con síndrome febril importado: estudio de cohortes retrospectivo.
dc.creator.none.fl_str_mv López-Amorós AI
Torrús-Tendero D
Merino De Lucas E
Reus Bañuls S
Boix Martínez V
Llorens Soriano P
Escribano Cañadas I
Ramos-Rincón JM
author López-Amorós AI
author_facet López-Amorós AI
Torrús-Tendero D
Merino De Lucas E
Reus Bañuls S
Boix Martínez V
Llorens Soriano P
Escribano Cañadas I
Ramos-Rincón JM
author_role author
author2 Torrús-Tendero D
Merino De Lucas E
Reus Bañuls S
Boix Martínez V
Llorens Soriano P
Escribano Cañadas I
Ramos-Rincón JM
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Arboviral diseases.
Arboviriasis.
Dengue.
Enfermedades relacionadas con el viaje.
Fever.
Fiebre.
Malaria.
Medicina del viajero.
Travel medicine.
Travel-related disease.
Travel.
Viajero.
topic Arboviral diseases.
Arboviriasis.
Dengue.
Enfermedades relacionadas con el viaje.
Fever.
Fiebre.
Malaria.
Medicina del viajero.
Travel medicine.
Travel-related disease.
Travel.
Viajero.
description OBJECTIVES: To identify predictors of malaria and arboviral disease in patients with febrile syndrome who seek care after traveling from tropical or subtropical locations. MATERIAL AND METHODS: Observational retrospective cohort study. We collected demographic, epidemiologic, and clinical data; laboratory findings; and the clinical and final microbiologic diagnoses. Multivariate analysis was used to calculate indices of diagnostic accuracy (sensitivity, specificity, and predictive values) and coefficients of probability of combinations of variables. RESULTS: Data for 291 patients with febrile syndrome were included; 108 had malaria (37.1%), 28 had an arboviral disease (9.6%), and 155 had other causes of fever (53.3%). Multivariate analysis showed patients most likely to have malaria were those from sub-Saharan Africa, adjusted odds ratio (aOR) of 45.85 (95% CI, 9.45-222.49); immigrants who returned to visit friends and relatives (VFR), aOR of 3.55 (95% CI, 1.21-10.46); or had platelet concentrations 150 000/mm3, aORa of 16.47 (95% CI, 5.46-49.70) or headache, aOR of 10.62 (95% CI, 3.20-35.28). The combination of these 4 variables gave a positive probability coefficient (PPC) of 23.72 (95% CI, 5.76-97.62). Patients with febrile syndrome most likely to have an arboviral disease were those from Central or South America, OR 5.07 (95% CI, 1.73-14.92), and those who had exanthems, OR 5.10 (95% CI, 1.72-17.02) or joint pain, OR 14.50 (95% CI, 3.05-68.80). The combination of these 3 variables gave a PPC of 20.66 (95% CI, 7.74-55.21). CONCLUSION: Patients with febrile syndrome with the greatest probability of having malaria are those from sub-Saharan Africa, those who are VFR, and those with platelet concentrations under 150.000/µL or headache. Arboviral disease was more likely in patients from Central and South America who had exanthems or joint pain.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://isabial.portalinvestigacion.com/publicaciones9589
http://emergencias.portalsemes.org/descargar/factores-asociados-con-malaria-y-arboviriasis-en-pacientes-con-sndrome-febril-importado-estudio-de-cohortes-retrospectivo/
url https://isabial.portalinvestigacion.com/publicaciones9589
http://emergencias.portalsemes.org/descargar/factores-asociados-con-malaria-y-arboviriasis-en-pacientes-con-sndrome-febril-importado-estudio-de-cohortes-retrospectivo/
dc.language.none.fl_str_mv Español
language_invalid_str_mv Español
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Soc Espanola Medicina Urgencias & Emergencias-SEMES
publisher.none.fl_str_mv Soc Espanola Medicina Urgencias & Emergencias-SEMES
dc.source.none.fl_str_mv Emergencias
ISSN: 11376821
ISSNe: 23865857
reponame:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
instname_str Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
reponame_str r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
collection r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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