Surface treatment of titanium with antibacterial properties for biomedical applications
Titanium, thanks to its good mechanical properties and an excellent biocompatibility and osseointegration, is used in the manufacture of dental implants. Nevertheless, after insertion into the human body, these implants can cause some issues such as periimplantitis, an inflammatory reaction caused b...
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| Tipo de recurso: | tesis de maestría |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universitat Politècnica de Catalunya (UPC) |
| Repositorio: | UPCommons. Portal del coneixement obert de la UPC |
| Idioma: | inglés |
| OAI Identifier: | oai:upcommons.upc.edu:2117/346100 |
| Acceso en línea: | https://hdl.handle.net/2117/346100 |
| Access Level: | acceso abierto |
| Palabra clave: | Implants, Artificial Titanium Implant dentures Titani Implants artificials Implants dentals Àrees temàtiques de la UPC::Enginyeria dels materials |
| Sumario: | Titanium, thanks to its good mechanical properties and an excellent biocompatibility and osseointegration, is used in the manufacture of dental implants. Nevertheless, after insertion into the human body, these implants can cause some issues such as periimplantitis, an inflammatory reaction caused by a microbial biofilm, which leads to the progressive loss of the implant. Thus, the objective of this project is to carry out different surface treatments of titanium used in biomedical applications in order to study the influence of surface properties, especially roughness, on bacterial adhesion. First of all, the main surface treatments with their advantages, limitations and parameters to be controlled were discussed. In this project, three were carried out, namely 'Sandblasting', 'SLA (Sandblasting, Large-grit, Acid Etching)’ and 'Alkali treatment'. Before these treatments, the titanium discs were polished. At the end, nine different surfaces were produced. The samples were observed with a Scanning Electron Microscope (SEM) and characterised in terms of roughness and surface energy. The topography and surface roughness were studied with equipment using the Chromatic Confocal principle. In addition, the surface tension was calculated using the Fowkes' theory on a contact angle database, obtained thanks to three different probe liquids (water, diiodomethane and formamide). The bacterial adhesion on these surfaces was then studied. Furthermore, the bacteria were fixed and observed at the SEM. After analysing the results, a correlation between surface roughness and bacterial adhesion was noticed: the rougher the surface increases, the more bacteria adhere to it. Moreover, bacteria adhere mainly in grooves and holes in the case of rough surfaces. High roughness provides a larger surface for bacteria adhesion. Thereby, smooth surfaces are more difficult to colonize than rough surfaces. On the other hand, it has been shown that surfaces that have undergone an Alkali treatment are super-hydrophilic. |
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