Association of alcohol consumption with coronary artery disease severity

Background & aims The ingestion of small to moderate alcohol consumption amounts has been associated to cardiovascular protection. This study aimed to evaluate the association between alcohol consumption and coronary artery disease severity. Material and methods Cross-sectional Study with patien...

Descripción completa

Detalles Bibliográficos
Autores: Chagas P., Mazocco L., Piccoli J.D.C.E., Ardenghi T.M., Badimon L., Caramori P.R.A., Pellanda L., Gomes I., Schwanke C.H.A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p10659
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10659
https://hdl.handle.net/10923/22650
Access Level:acceso abierto
Palabra clave:alcohol
adult
age
alcohol abuse
alcohol consumption
Article
cardiovascular risk
coronary angiography
coronary artery disease
cross-sectional study
diabetes mellitus
disease association
disease severity
drinking behavior
dyslipidemia
female
human
hypertension
major clinical study
male
smoking
aged
alcohol abstinence
alcoholism
Brazil
comparative study
coronary blood vessel
diagnostic imaging
hospital
middle aged
pathophysiology
risk factor
self report
severity of illness index
very elderly
young adult
Adult
Aged
Aged, 80 and over
Alcohol Abstinence
Alcohol Drinking
Alcoholism
Coronary Angiography
Coronary Artery Disease
Coronary Vessels
Cross-Sectional Studies
Female
Hospitals, Urban
Humans
Male
Middle Aged
Risk Factors
Self Report
Severity of Illness Index
Young Adult
Descripción
Sumario:Background & aims The ingestion of small to moderate alcohol consumption amounts has been associated to cardiovascular protection. This study aimed to evaluate the association between alcohol consumption and coronary artery disease severity. Material and methods Cross-sectional Study with patients undergoing coronary angiography. Age, cardiovascular risk factors (smoking, systemic arterial hypertension, dyslipidemia and diabetes) and alcohol drinking habit were investigated. Alcohol consumption was divided in three categories: nondrinker, moderate alcohol consumption (less than 15 g ethanol/day for women or 30 g ethanol/day for men) and heavy alcohol consumption. Coronary artery disease severity was assessed through the Friesinger Score (FS) in the coronary angiography, by interventional cardiologists blinded to alcohol consumption. Results The final sample included 363 adults; of those, 228 were men (62.81%). Mean age was 60.5 ± 10.9 y. Unadjusted analyses identified sex, age, hypertension, diabetes, dyslipidemia and alcohol consumption as the main covariates associated with the Friesinger score. Lower Friesinger scores were also observed in moderate alcohol consumption when comparing to those who do not drink (RR 0.86; 95% CI 0.79–0.95). Conclusion Among patients with suspected coronary artery disease undergoing coronary angiography, moderate alcohol consumption is associated to a lower coronary artery disease severity than heavy drinking. © 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism