Individual nodeʼs contribution to the mesoscale of complex networks

The analysis of complex networks is devoted to the statistical characterization of/nthe topology of graphs at different scales of organization in order to understand/ntheir functionality. While the modular structure of networks has become an/nessential element to better apprehend their complexity, t...

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Detalles Bibliográficos
Autores: Klimm, Florian, Borge-Holthoefer, Javier, Wessel, Niels, Kurths, Jürgen, Zamora-López, Gorka
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/25903
Acceso en línea:http://hdl.handle.net/10230/25903
http://dx.doi.org/10.1088/1367-2630/16/12/125006
Access Level:acceso abierto
Palabra clave:Network metrics
Community structure
Neuronal networks
Genetic regulatory networks
Descripción
Sumario:The analysis of complex networks is devoted to the statistical characterization of/nthe topology of graphs at different scales of organization in order to understand/ntheir functionality. While the modular structure of networks has become an/nessential element to better apprehend their complexity, the efforts to characterize/nthe mesoscale of networks have focused on the identification of the modules/nrather than describing the mesoscale in an informative manner. Here we propose/na framework to characterize the position every node takes within the modular/nconfiguration of complex networks and to evaluate their function accordingly./nFor illustration, we apply this framework to a set of synthetic networks,/nempirical neural networks, and to the transcriptional regulatory network of the/nMycobacterium tuberculosis.Wefind that the architecture of both neuronal and/ntranscriptional networks are optimized for the processing of multisensory information with the coexistence of well-de/nfined modules of specialized components and the presence of hubs conveying information from and to the/ndistinct functional domains