Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project

Background: Information of the epidemiology of Major Depressive Episode (MDE) in Spain, one of the biggest southern European countries, is scarce and heterogeneous. The objective of this study was to assess the epidemiology of the disorder in the Spanish sample of the ESEMeD project. Methods: The ES...

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Authors: Gabilondo Cuéllar, Andrea, Rojas Farreras, Sonia, Vilagut Saiz, Gemma, 1975-, Haro Abad, Josep Maria, Fernández Sánchez, Ana, Pinto Meza, Alejandra, Alonso Caballero, Jordi
Format: article
Status:Versión aceptada para publicación
Publication Date:2010
Country:España
Institution:Universitat Pompeu Fabra
Repository:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/36824
Online Access:http://hdl.handle.net/10230/36824
http://dx.doi.org/10.1016/j.jad.2009.04.016
Access Level:Open access
Keyword:Depressió psíquica
Epidemiologia
Enquestes
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spelling Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain projectGabilondo Cuéllar, AndreaRojas Farreras, SoniaVilagut Saiz, Gemma, 1975-Haro Abad, Josep MariaFernández Sánchez, AnaPinto Meza, AlejandraAlonso Caballero, JordiDepressió psíquicaEpidemiologiaEnquestesBackground: Information of the epidemiology of Major Depressive Episode (MDE) in Spain, one of the biggest southern European countries, is scarce and heterogeneous. The objective of this study was to assess the epidemiology of the disorder in the Spanish sample of the ESEMeD project. Methods: The ESEMED-Spain project is a cross-sectional, general population, household survey conducted with a representative sample of Spanish non-institutionalized adult population. The survey instrument was the CIDI 3.0, a structured diagnostic interview to assess disorders and treatment. Results: Lifetime prevalence was 10.6% while 12-month prevalence was 4.0%. A monotonic increase in lifetime overall prevalence was found from the youngest to the 50–64 cohort, declining then in the oldest group. Median age of onset was 30.0. Being a woman (OR= 2.7), previously married (OR= 1.8), unemployed or disabled to work (OR= 2.9) was associated to higher risk of 12-month-MDE. The highest comorbid associations were with dysthymia (OR= 73.1) and panic disorder (OR= 41.8). Limitations: 1. Psychiatric diagnoses were made by trained lay interviewers and this could have an imperfect sensitivity/specificity; 2. Individuals with mental illness could have more frequently rejected to participate in the survey; 3. Age-related recall bias could have affected the accuracy of age of onset estimates. Conclusions: The study shows that prevalence MDE in Spain is lower than in other Western countries. Important findings are the early age of onset, the high proportion of chronicity, and the high female/male ratio. Taken together, results offer a complex picture of the epidemiology of MDE in Spain, when compared to other countries in Europe. The role of cultural factors is discussed.The ESEMeD project (http://www.epremed.org) was funded by the European Commission (Contracts QLG5- 1999-01042; SANCO 2004123), the Piedmont Region (Italy), Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spain (FIS 00/0028-02), Ministerio de Ciencia y Tecnología, Spain (SAF 2000-158-CE), Departament de Salut, Generalitat de Catalunya, Spain. These activities were supported by the United States National Institute of Mental Health (R01MH070884, MH077883), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the US Public Health Service (R13-MH066849, R01-MH069864, and R01 DA016558), the Fogarty International Center (FIRCA R03-TW006481)Elsevier201920192010info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/36824http://dx.doi.org/10.1016/j.jad.2009.04.016reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésJournal of Affective Disorders. 2010 Jan;120(1-3):76-85© Elsevier http://dx.doi.org/10.1016/j.jad.2009.04.016info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/368242026-06-12T07:21:37Z
dc.title.none.fl_str_mv Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
title Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
spellingShingle Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
Gabilondo Cuéllar, Andrea
Depressió psíquica
Epidemiologia
Enquestes
title_short Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
title_full Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
title_fullStr Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
title_full_unstemmed Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
title_sort Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project
dc.creator.none.fl_str_mv Gabilondo Cuéllar, Andrea
Rojas Farreras, Sonia
Vilagut Saiz, Gemma, 1975-
Haro Abad, Josep Maria
Fernández Sánchez, Ana
Pinto Meza, Alejandra
Alonso Caballero, Jordi
author Gabilondo Cuéllar, Andrea
author_facet Gabilondo Cuéllar, Andrea
Rojas Farreras, Sonia
Vilagut Saiz, Gemma, 1975-
Haro Abad, Josep Maria
Fernández Sánchez, Ana
Pinto Meza, Alejandra
Alonso Caballero, Jordi
author_role author
author2 Rojas Farreras, Sonia
Vilagut Saiz, Gemma, 1975-
Haro Abad, Josep Maria
Fernández Sánchez, Ana
Pinto Meza, Alejandra
Alonso Caballero, Jordi
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Depressió psíquica
Epidemiologia
Enquestes
topic Depressió psíquica
Epidemiologia
Enquestes
description Background: Information of the epidemiology of Major Depressive Episode (MDE) in Spain, one of the biggest southern European countries, is scarce and heterogeneous. The objective of this study was to assess the epidemiology of the disorder in the Spanish sample of the ESEMeD project. Methods: The ESEMED-Spain project is a cross-sectional, general population, household survey conducted with a representative sample of Spanish non-institutionalized adult population. The survey instrument was the CIDI 3.0, a structured diagnostic interview to assess disorders and treatment. Results: Lifetime prevalence was 10.6% while 12-month prevalence was 4.0%. A monotonic increase in lifetime overall prevalence was found from the youngest to the 50–64 cohort, declining then in the oldest group. Median age of onset was 30.0. Being a woman (OR= 2.7), previously married (OR= 1.8), unemployed or disabled to work (OR= 2.9) was associated to higher risk of 12-month-MDE. The highest comorbid associations were with dysthymia (OR= 73.1) and panic disorder (OR= 41.8). Limitations: 1. Psychiatric diagnoses were made by trained lay interviewers and this could have an imperfect sensitivity/specificity; 2. Individuals with mental illness could have more frequently rejected to participate in the survey; 3. Age-related recall bias could have affected the accuracy of age of onset estimates. Conclusions: The study shows that prevalence MDE in Spain is lower than in other Western countries. Important findings are the early age of onset, the high proportion of chronicity, and the high female/male ratio. Taken together, results offer a complex picture of the epidemiology of MDE in Spain, when compared to other countries in Europe. The role of cultural factors is discussed.
publishDate 2010
dc.date.none.fl_str_mv 2010
2019
2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/36824
http://dx.doi.org/10.1016/j.jad.2009.04.016
url http://hdl.handle.net/10230/36824
http://dx.doi.org/10.1016/j.jad.2009.04.016
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Journal of Affective Disorders. 2010 Jan;120(1-3):76-85
dc.rights.none.fl_str_mv © Elsevier http://dx.doi.org/10.1016/j.jad.2009.04.016
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © Elsevier http://dx.doi.org/10.1016/j.jad.2009.04.016
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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