Dysmorphic uteri: Obstetric results after hysteroscopic office metroplasty in infertile and recurrent pregnancy loss patients. A prospective observational study

To compare the obstetric results achieved after hysteroscopic office metroplasty (HOME-DU) in infertile and recurrent pregnancy loss (RPL) patients diagnosed with dysmorphic uterus, women hysteroscopically diagnosed with dysmorphic uterus who underwent uterine-enlargement metroplasty were prospectiv...

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Detalles Bibliográficos
Autores: Sánchez-Santiuste, Mónica, Ríos Vallejo, María del Mar, Calles Sastre, Laura Beatriz, Cuesta Benjumea, María de los Reyes de la, Engels Calvo, Virginia, Pereira Sánchez, Augusto, Pérez Medina, Tirso
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/695603
Acceso en línea:http://hdl.handle.net/10486/695603
https://dx.doi.org/10.3390/jcm9092857
Access Level:acceso abierto
Palabra clave:dysmorphic uterus
hypoplastic uterus
T-shaped uterus
uterine malformation
Müllerian anomaly
hysteroscopy
HOME-DU
metroplasty
infertility
recurrent pregnancy loss
Medicina
Descripción
Sumario:To compare the obstetric results achieved after hysteroscopic office metroplasty (HOME-DU) in infertile and recurrent pregnancy loss (RPL) patients diagnosed with dysmorphic uterus, women hysteroscopically diagnosed with dysmorphic uterus who underwent uterine-enlargement metroplasty were prospectively enrolled from June 2016 until April 2020. Patients were followed up and obstetric outcomes were recorded (pregnancy and live birth rate). Sixty-three women (30 infertile; 33 RPL) were enrolled, of which 48 became pregnant post-HOME-DU, with an overall pregnancy rate of 76.2% (66.7% among infertile participants; 84.9% among those with RPL). Overall, 64.3% (n = 36/63) achieved live birth. Among infertile women, 62.07% (n = 18/29) achieved live birth, as well as 66.7% of women with RPL (n = 18/27). The di erence in live birth rates between both cohorts was 4.6% (p > 0.05). The rate of miscarriage amongst infertile patients was 3.3% (n = 1/30) and 12.1% amongst women with RPL (n = 4/33). Office metroplasty via the HOME-DU technique improves obstetric results (namely increasing live birth rate) in patients with dysmorphic uterus and a history of reproductive failure. No significant difference was found in the clinical efficacy of HOME-DU in infertile and RPL patients