DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer.

DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in metastatic colorectal cancer.

Detalles Bibliográficos
Autores: Martinez-Useros, Javier, Rodriguez-Remirez, Maria, Borrero-Palacios, Aurea, Moreno, Irene, Cebrian, Arancha, Gomez del Pulgar, Teresa, del Puerto-Nevado, Laura, Vega-Bravo, Ricardo, Puime-Otin, Alberto, Perez, Nuria, Zazo, Sandra, Senin, Clara, Fernandez-Aceñero, Maria J, Soengas, MS, Rojo, Federico, Garcia-Foncillas, Jesus
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/25424
Acceso en línea:https://hdl.handle.net/20.500.12105/25424
Access Level:acceso abierto
Palabra clave:DEK
Irinotecan
Aggressive phenotype
Metastatic colorectal cancer
KRAS
Descripción
Sumario:DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in metastatic colorectal cancer.

Similares en LA Referencia