The Independent Effects of Psychosocial Stressors on Subclinical Psychosis: Findings From the Multinational EU-GEI Study.

The influence of psychosocial stressors on psychosis risk has usually been studied in isolation and after the onset of the disorder, potentially ignoring important confounding relationships or the fact that some stressors that may be the consequence of the disorder rather than preexisting. The study...

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Detalles Bibliográficos
Autores: Pignon, Baptiste, Lajnef, Mohamed, Kirkbride, James B, Peyre, Hugo, Ferchiou, Aziz, Richard, Jean-Romain, Baudin, Gregoire, Tosato, Sarah, Jongsma, Hannah, de Haan, Lieuwe, Tarricone, Ilaria, Bernardo, Miguel, Velthorst, Eva, Braca, Mauro, Arango, Celso, Arrojo, Manuel, Bobes, Julio, Del-Ben, Cristina Marta, Di Forti, Marta, Gayer-Anderson, Charlotte, Jones, Peter B, La Cascia, Caterina, Lasalvia, Antonio, Menezes, Paulo Rossi, Quattrone, Diego, Sanjuan, Julio, Selten, Jean-Paul, Tortelli, Andrea, Llorca, Pierre-Michel, van Os, Jim, Rutten, Bart P F, Murray, Robin M, Morgan, Craig, Leboyer, Marion, Szoke, Andrei, Schurhoff, Franck
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p15786
Acceso en línea:https://incliva.portalinvestigacion.com/publicaciones/15786
Access Level:acceso abierto
Palabra clave:Community Assessment of Psychic Experiences (CAPE)
childhood trauma
depressive subclinical symptoms
discrimination
negative subclinical symptoms
positive subclinical symptoms
psychosocial stress
psychotic symptoms
schizotypy
social capital
stressful life events
subclinical psychosis
Descripción
Sumario:The influence of psychosocial stressors on psychosis risk has usually been studied in isolation and after the onset of the disorder, potentially ignoring important confounding relationships or the fact that some stressors that may be the consequence of the disorder rather than preexisting. The study of subclinical psychosis could help to address some of these issues. In this study, we investigated whether there was (i) an association between dimensions of subclinical psychosis and several psychosocial stressors including: childhood trauma, self-reported discrimination experiences, low social capital, and stressful life experiences, and (ii) any evidence of environment-environment (ExE) interactions between these factors. Data were drawn from the EUGEI study, in which healthy controls (N = 1497) and siblings of subjects with a psychotic disorder (N = 265) were included in six countries. The association between psychosocial stressors and subclinical psychosis dimensions (positive, negative and depressive dimension as measured by the Community Assessment of Psychic Experiences (CAPE) scale) and possible ExE interactions were assessed using linear regression models. After adjusting for sex, age, ethnicity, country, and control/sibling status, childhood trauma (ß for positive dimension: 0.13, negative: 0.49, depressive: 0.26) and stressful life events (positive: 0.08, negative: 0.16, depressive: 0.17) were associated with the three dimensions. Lower social capital was associated with the negative and depression dimensions (negative: 0.26, depressive: 0.13), and self-reported discrimination experiences with the positive dimension (0.06). Our findings are in favor of independent, cumulative and non-specific influences of social adversities in subclinical psychosis in non-clinical populations, without arguments for E × E interactions.

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