Low-density lipoprotein cholesterol and suicidal behaviour in a large sample of first-episode psychosis patients

Objectives: Our aims were to confirm the relationship between lipid and lipoprotein concentrations and suicidal behaviour in first-episode psychosis (FEP) patients. Methods: Suicidal behaviour was explored in a large FEP sample (N?=?383). Baseline lipid profile was compared between those who attempt...

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Detalles Bibliográficos
Autores: Ayesa Arriola, Rosa, Canal Rivero, Manuel, Delgado Alvarado, Manuel, Setién Suero, María Esther, González Gómez, Jana, Labad, Javier, David, Anthony S., Crespo Facorro, Benedicto|||0000-0001-9709-1276
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/15309
Acceso en línea:http://hdl.handle.net/10902/15309
Access Level:acceso abierto
Palabra clave:Cholesterol
First Episode Psychosis
Lipoproteins
Schizophrenia
Suicide
Descripción
Sumario:Objectives: Our aims were to confirm the relationship between lipid and lipoprotein concentrations and suicidal behaviour in first-episode psychosis (FEP) patients. Methods: Suicidal behaviour was explored in a large FEP sample (N?=?383). Baseline lipid profile was compared between those who attempted or completed suicide and those who not presented suicidal behaviour. Results: Low-density lipoprotein cholesterol (LDL-c) (OR?=?0.99, 95% CI=?0.98?1.00) and depressive symptoms (OR?=?1.15, 95% CI?=?1.06?1.24) were significantly related with suicidal behaviour. Conclusions: Lipid profile test may be considered in the assessment of suicide risk in psychosis and LDL-c an important biological marker.