Enzymatic technology for the production of high added value oligomers from natural antioxidants

The undeniable shift to worldwide aged population and the increasing attraction of consumers towards natural products has induced a growing demand of polyphenolic antioxidants. However, the applicability of these substances is often hindered by their scarce bioavailability. The enzymatic polymerizat...

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Bibliographic Details
Author: Muñiz Mouro, Abel
Format: doctoral thesis
Publication Date:2022
Country:España
Institution:Universidad de Santiago de Compostela (USC)
Repository:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Language:English
OAI Identifier:oai:minerva.usc.gal:10347/28748
Online Access:http://hdl.handle.net/10347/28748
Access Level:Open access
Keyword:Materias::Investigación::33 Ciencias tecnológicas::3302 Tecnología bioquímica::330290 Ingeniería bioquímica
Materias::Investigación::33 Ciencias tecnológicas::3303 ingeniería y tecnología químicas::330303 Procesos químicos
Description
Summary:The undeniable shift to worldwide aged population and the increasing attraction of consumers towards natural products has induced a growing demand of polyphenolic antioxidants. However, the applicability of these substances is often hindered by their scarce bioavailability. The enzymatic polymerization of these compounds has been proven an efficient method leading to products with enhanced aqueous solubility. The present PhD thesis focuses on the oligomerization of natural antioxidants with pharmacological and nutraceutical properties, catalyzed by fungal enzymes. The achieved results allowed to identify the operational parameters affecting the properties of the obtained oligomers, as well as to perform a preliminary environmental and economic assessment of the reuse of the biocatalyst in biocompatible reaction media.