[Cerebral cavernomas. A review and update of aetiological, clinical and therapeutic features]

Introduction: Cavernous angiomas are uncommon lesions, with a reported incidence of 0.4 to 0.8%, presenting a controversial management especially regarding their surgical treatment. Aim: To update cavernous angiomas characteristics and management through a deep review of the literature concerning th...

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Detalles Bibliográficos
Autores: Iza, Begoña, Mateo Sierra, Olga, Mosqueira, Bernardo, Ruiz Juretschke, Fernando, Carrillo Yagüe, Rafael
Tipo de recurso: artículo
Fecha de publicación:2005
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:español
OAI Identifier:oai:docta.ucm.es:20.500.14352/129341
Acceso en línea:https://hdl.handle.net/20.500.14352/129341
Access Level:acceso abierto
Palabra clave:616.8
Cavernoma
Cavernous angioma
Cavernous hemangioma
Familiar cavernomatosis
Vascular hamartoma.
Ciencias Biomédicas
32 Ciencias Médicas
Descripción
Sumario:Introduction: Cavernous angiomas are uncommon lesions, with a reported incidence of 0.4 to 0.8%, presenting a controversial management especially regarding their surgical treatment. Aim: To update cavernous angiomas characteristics and management through a deep review of the literature concerning their aetiology, epidemiology, history, signs and symptoms, diagnosis, and surgical and radiosurgical treatment. Development and conclusions: Most important advances found in the recent literature include the identification of the genetic basis responsible for the familial form of cavernomatosis (CCM1, CCM2 and CCM3), the identification of the dynamic pattern of these lesions based on their pathology and imaging features, the deeper knowledge on their natural history depending on their supra/infratentorial location, and the main indications for surgical treatment and radiosurgical therapy suggested by the recent series.