Neural dynamics underlying object and action naming across languages: Insights from health and disease

91 p.

Detalles Bibliográficos
Autor: Geng, Shuang
Tipo de recurso: tesis doctoral
Fecha de publicación:2023
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/64857
Acceso en línea:http://hdl.handle.net/10810/64857
Access Level:acceso abierto
Palabra clave:human neuro-anatomy
bilinguism
brain function
neuroanatomía humana
bilingüismo
función cerebral
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spelling Neural dynamics underlying object and action naming across languages: Insights from health and diseaseGeng, Shuanghuman neuro-anatomybilinguismbrain functionneuroanatomía humanabilingüismofunción cerebral91 p.Words representing objects (nouns) and words representing actions (verbs) are essential components of speech across languages. Previous studies have shown that the lexico-semantic processing of object and action knowledge depends on segregated ventral and dorsal pathways, respectively involving inferotemporal and frontoparietal nodes. Despite extensive research, a comprehensive understanding of the neural dynamics (including spatial, temporal, and spectral patterns) underlying this process and its potential variation across languages is currently missing. Furthermore, evidence supporting its functional reorganization in the presence of brain damage is scarse. This doctoral thesis addresses two critical questions: (1) What are the neural signatures of object and action naming across different languages? (2) How does the presence of brain tumors affecting ventral and dorsal pathways impact on the lexico-semantic processing of object and action knowledge? To answer these questions, we collected behavioral and MEG data while participants performed a picture-naming task, the gold standard for investigating speech production. We evaluated healthy monolingual and bilingual speakers, and brain tumor patients with low-grade gliomas in ventral and dorsal regions, both before and after surgery for tumor resection. Results from healthy participants showed segregated beta (13¿28 Hz) power decreases in left ventral and dorsal pathways for object and action naming. These modulations occurred during a time-window associated with lexico-semantic processing (~250-500ms), supporting the notion that speech production involves partially different networks depending on the semantic category being processed. Interestingly, we found that these neural patterns overlapped across different languages (Spanish and Basque) in highly proficient bilingual speakers, suggesting that when individuals master both languages to a similar extent, category-based representations overlap at the semantic level. Finally, when longitudinally comparing patients' responses (post- vs. pre-surgery) we found beta modulations mimicking the category¿based segregation showed by healthy individuals, with ventral and dorsal damage leading to selective compensation for object and action naming, respectively. A similar pattern was also observed in bilingual patients. Overall, these findings have important theoretical and clinical implications for language (re)organization in health and disease.Carreiras Valiña, Manuel FranciscoAmoruso, Lucía2024202420232023info:eu-repo/semantics/doctoralThesisapplication/pdfhttp://hdl.handle.net/10810/64857reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoInglésinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/es/Atribución 3.0 Españaoai:addi.ehu.eus:10810/648572026-06-18T09:23:17Z
dc.title.none.fl_str_mv Neural dynamics underlying object and action naming across languages: Insights from health and disease
title Neural dynamics underlying object and action naming across languages: Insights from health and disease
spellingShingle Neural dynamics underlying object and action naming across languages: Insights from health and disease
Geng, Shuang
human neuro-anatomy
bilinguism
brain function
neuroanatomía humana
bilingüismo
función cerebral
title_short Neural dynamics underlying object and action naming across languages: Insights from health and disease
title_full Neural dynamics underlying object and action naming across languages: Insights from health and disease
title_fullStr Neural dynamics underlying object and action naming across languages: Insights from health and disease
title_full_unstemmed Neural dynamics underlying object and action naming across languages: Insights from health and disease
title_sort Neural dynamics underlying object and action naming across languages: Insights from health and disease
dc.creator.none.fl_str_mv Geng, Shuang
author Geng, Shuang
author_facet Geng, Shuang
author_role author
dc.contributor.none.fl_str_mv Carreiras Valiña, Manuel Francisco
Amoruso, Lucía
dc.subject.none.fl_str_mv human neuro-anatomy
bilinguism
brain function
neuroanatomía humana
bilingüismo
función cerebral
topic human neuro-anatomy
bilinguism
brain function
neuroanatomía humana
bilingüismo
función cerebral
description 91 p.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/64857
url http://hdl.handle.net/10810/64857
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/es/
Atribución 3.0 España
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/3.0/es/
Atribución 3.0 España
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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