Malignancies in Prader-Willi Syndrome: Results From a Large International Cohort and Literature Review.

Prader-Willi syndrome (PWS) is a complex disorder combining hypothalamic dysfunction, neurodevelopmental delay, hypotonia, and hyperphagia with risk of obesity and its complications. PWS is caused by the loss of expression of the PWS critical region, a cluster of paternally expressed genes on chromo...

Descripción completa

Detalles Bibliográficos
Autores: Pellikaan K, Nguyen NQC, Rosenberg AGW, Coupaye M, Goldstone AP, Høybye C, Markovic T, Grugni G, Crinò A, Caixàs A, Poitou C, Corripio R, Nieuwenhuize RM, van der Lely AJ, de Graaff LCG
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p4213
Acceso en línea:https://i3pt.portalinvestigacion.com/publicaciones/4213
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85177103492&doi=10.1210%2fclinem%2fdgad312&partnerID=40&md5=34c653dbfb6351415e1ed91ac716aebf
Access Level:acceso abierto
Palabra clave:Prader-Willi syndrome, comorbidity, hypothalamo-hypophyseal system, neoplasms
Descripción
Sumario:Prader-Willi syndrome (PWS) is a complex disorder combining hypothalamic dysfunction, neurodevelopmental delay, hypotonia, and hyperphagia with risk of obesity and its complications. PWS is caused by the loss of expression of the PWS critical region, a cluster of paternally expressed genes on chromosome 15q11.2-q13. As life expectancy of patients with PWS increases, age-related diseases like malignancies might pose a new threat to health.

Similares en LA Referencia