Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice

Purpose: to ascertain wet AMD (wAMD) management patterns in Spain. Methods: a two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results: forty-nine retina specialists experienced in wAMD participa...

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Detalles Bibliográficos
Autores: García Layana, Alfredo, García Arumí, José, Figueroa, Marta S., Arias Barquet, Lluís, Ruiz Moreno, José María, 1958-, Monclús, Laura, The Spanish AMD Multicenter Group
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/173775
Acceso en línea:https://hdl.handle.net/2445/173775
Access Level:acceso abierto
Palabra clave:Degeneració (Patologia)
Malalties de la retina
Espanya
Degeneration (Pathology)
Retinal diseases
Spain
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spelling Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practiceGarcía Layana, AlfredoGarcía Arumí, JoséFigueroa, Marta S.Arias Barquet, LluísRuiz Moreno, José María, 1958-Monclús, LauraThe Spanish AMD Multicenter GroupDegeneració (Patologia)Malalties de la retinaEspanyaDegeneration (Pathology)Retinal diseasesSpainPurpose: to ascertain wet AMD (wAMD) management patterns in Spain. Methods: a two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results: forty-nine retina specialists experienced in wAMD participated by answering the two-round study questionnaire. Retina specialists are the main responsible for wAMD diagnosis and monitoring, including visits and associated procedures, with a median time per visit of 15 minutes. Standard treatment strategies are based on anti-VEGF administration, including standard loading dose administration followed by maintenance with aflibercept or ranibizumab (81% of patients). Although treat and extend (T&E) dosing strategy is considered as optimal for wAMD management (78% of the panelists), the main routine healthcare limitations (i.e., visits overload, reduced staff, short visit time, coordination issues, lack of facilities) conduct to self-defined "flexible" strategies, based on T&E and pro-re-nata (PRN) protocols. Conclusion: proactive treatment patterns (T&E) are the preferred ones by the retina specialists in Spain. However, their proper implementation is difficult due to healthcare resource limitations, as well as organisation and logistic issues. The use of anti-VEGF agents with longer duration of action could facilitate the use of strict T&E approaches according to routine clinical practices.Hindawi2021202120192021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion11 p.application/pdfhttps://hdl.handle.net/2445/173775Articles publicats en revistes (Ciències Clíniques)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1155/2019/9821509Journal of Ophthalmology, 2019, vol. 2019, p. 9821509https://doi.org/10.1155/2019/9821509cc-by (c) García Layana, Alfredo et al., 2019http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/1737752026-05-29T05:05:01Z
dc.title.none.fl_str_mv Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
title Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
spellingShingle Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
García Layana, Alfredo
Degeneració (Patologia)
Malalties de la retina
Espanya
Degeneration (Pathology)
Retinal diseases
Spain
title_short Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
title_full Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
title_fullStr Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
title_full_unstemmed Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
title_sort Management of wet age-related macular degeneration in Spain: challenges for treat and extend implementation in routine clinical practice
dc.creator.none.fl_str_mv García Layana, Alfredo
García Arumí, José
Figueroa, Marta S.
Arias Barquet, Lluís
Ruiz Moreno, José María, 1958-
Monclús, Laura
The Spanish AMD Multicenter Group
author García Layana, Alfredo
author_facet García Layana, Alfredo
García Arumí, José
Figueroa, Marta S.
Arias Barquet, Lluís
Ruiz Moreno, José María, 1958-
Monclús, Laura
The Spanish AMD Multicenter Group
author_role author
author2 García Arumí, José
Figueroa, Marta S.
Arias Barquet, Lluís
Ruiz Moreno, José María, 1958-
Monclús, Laura
The Spanish AMD Multicenter Group
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Degeneració (Patologia)
Malalties de la retina
Espanya
Degeneration (Pathology)
Retinal diseases
Spain
topic Degeneració (Patologia)
Malalties de la retina
Espanya
Degeneration (Pathology)
Retinal diseases
Spain
description Purpose: to ascertain wet AMD (wAMD) management patterns in Spain. Methods: a two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results: forty-nine retina specialists experienced in wAMD participated by answering the two-round study questionnaire. Retina specialists are the main responsible for wAMD diagnosis and monitoring, including visits and associated procedures, with a median time per visit of 15 minutes. Standard treatment strategies are based on anti-VEGF administration, including standard loading dose administration followed by maintenance with aflibercept or ranibizumab (81% of patients). Although treat and extend (T&E) dosing strategy is considered as optimal for wAMD management (78% of the panelists), the main routine healthcare limitations (i.e., visits overload, reduced staff, short visit time, coordination issues, lack of facilities) conduct to self-defined "flexible" strategies, based on T&E and pro-re-nata (PRN) protocols. Conclusion: proactive treatment patterns (T&E) are the preferred ones by the retina specialists in Spain. However, their proper implementation is difficult due to healthcare resource limitations, as well as organisation and logistic issues. The use of anti-VEGF agents with longer duration of action could facilitate the use of strict T&E approaches according to routine clinical practices.
publishDate 2019
dc.date.none.fl_str_mv 2019
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/173775
url https://hdl.handle.net/2445/173775
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1155/2019/9821509
Journal of Ophthalmology, 2019, vol. 2019, p. 9821509
https://doi.org/10.1155/2019/9821509
dc.rights.none.fl_str_mv cc-by (c) García Layana, Alfredo et al., 2019
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) García Layana, Alfredo et al., 2019
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 11 p.
application/pdf
dc.publisher.none.fl_str_mv Hindawi
publisher.none.fl_str_mv Hindawi
dc.source.none.fl_str_mv Articles publicats en revistes (Ciències Clíniques)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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