Microglia is an active player in how glibenclamide improves stroke outcome

The recent review article"Sulfonylurea receptor 1 in central nervous system injury: a focused review"1 is an extensive summary of the current knowledge of the role of the sulfonylurea receptor 1 (SUR-1) and SUR-1-regulated NCCa-ATP channels in acute brain injuries. The review also highligh...

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Detalhes bibliográficos
Autores: Ortega González, Fco. Javier, Jolkkonen, Jukka, Rodríguez Allué, Manuel José
Tipo de documento: artigo
Estado:Versión aceptada para publicación
Data de publicação:2013
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/57664
Acesso em linha:https://hdl.handle.net/2445/57664
Access Level:Acceso aberto
Palavra-chave:Isquèmia cerebral
Micròglia
Cerebral ischemia
Microglia
Descrição
Resumo:The recent review article"Sulfonylurea receptor 1 in central nervous system injury: a focused review"1 is an extensive summary of the current knowledge of the role of the sulfonylurea receptor 1 (SUR-1) and SUR-1-regulated NCCa-ATP channels in acute brain injuries. The review also highlights the potential translational applicability of the use of glibenclamide in treating brain pathologies such as cerebral ischemia or traumatic brain injury.......