The outer membranes of Brucella spp. are not barriers to hydrophobic permeants

The patterns of susceptibility to hydrophobic and hydrophilic drugs and the uptake of the fluorescent probe N-phenyl-naphthylamine in Brucella spp., Haemophilus influenzae, Escherichia coli, and deep rough Salmonella minnesota mutants were compared. The results show that the outer membranes of smoot...

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Detalles Bibliográficos
Autores: Martinez-de-Tejada, G. (Guillermo)|||/items/d1daba26-b84c-4914-8630-f3a980ec3bc8, Moriyon, I. (Ignacio)|||/items/834b4ce9-a879-4ba7-8884-39d0ddd88c7b
Tipo de recurso: artículo
Fecha de publicación:1993
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/29519
Acceso en línea:https://hdl.handle.net/10171/29519
Access Level:acceso abierto
Palabra clave:1-Naphthylamine analogs and derivatives
Brucella physiology
Cell Membrane physiology
Cell Membrane Permeability
Descripción
Sumario:The patterns of susceptibility to hydrophobic and hydrophilic drugs and the uptake of the fluorescent probe N-phenyl-naphthylamine in Brucella spp., Haemophilus influenzae, Escherichia coli, and deep rough Salmonella minnesota mutants were compared. The results show that the outer membranes of smooth and naturally rough Brucella spp. do not represent barriers to hydrophobic permeants and that this absence of a barrier relates at least in part to the properties of Brucella lipopolysaccharide.