Obstructive Sleep Apnea Syndrome (OSAS). Review of the literature

Obstructive sleep apnea and hypopnea syndrome is characterized by repeated airway collapse during sleep. The literature describes multiple causes of the disease. The main cause is a reduction of the expansion forces of the pharyngeal dilator muscles, as in situations of genioglossal muscle dysfuncti...

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Detalhes bibliográficos
Autores: Azagra Calero, Eva, Espinar-Escalona, E., Barrera Mora, José María, Llamas, J.M., Solano Reina, José Enrique
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:España
Recursos:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/33030
Acesso em linha:http://hdl.handle.net/11441/33030
https://doi.org/doi:10.4317/medoral.177
Access Level:acceso abierto
Palavra-chave:Sleep apnea
Obstructive sleep apnea
Sleep apnea syndrome
Ostructive sleep apnea syndrome
Descrição
Resumo:Obstructive sleep apnea and hypopnea syndrome is characterized by repeated airway collapse during sleep. The literature describes multiple causes of the disease. The main cause is a reduction of the expansion forces of the pharyngeal dilator muscles, as in situations of genioglossal muscle dysfunction, and discoordination between the inspiratory activity of the muscle and respiratory effort, which play an important role in progression of the disease. Other described causes are soft tissue disorders, such as macroglossia or tonsillar hypertrophy, and skeletal structural alterations such as micrognathia and retrognathia. The syndrome is also more frequent in obese people, where the accumulation of fat in the neck region produces narrowing of th pharyngeal airway, thereby diminishing the passage of air. This review focuses on the pathogenesis, epidemiology, main features and diagnosis of the disease, and on its main forms of treatment.