Phase angle in localized bioimpedance measurements to assess and monitor muscle injury

Localized bioimpedance (L-BIA) measurements are an innovative method to non-invasively identify structural derangement of soft tissues, principally muscles, and fluid accumulation in response to traumatic injury. This review provides unique L-BIA data demonstrating significant relative differences b...

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Autores: Nescolarde Selva, Lexa Digna|||0000-0001-6861-5106, Talluri, Antonio, Yanguas Leyes, Javier, Lukaski, Henry
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/386780
Acceso en línea:https://hdl.handle.net/2117/386780
https://dx.doi.org/10.1007/s11154-023-09790-9
Access Level:acceso abierto
Palabra clave:Muscles
Localized bioimpedance
Muscle
Reactance
Magnetic resonance imaging
Músculs
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
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spelling Phase angle in localized bioimpedance measurements to assess and monitor muscle injuryNescolarde Selva, Lexa Digna|||0000-0001-6861-5106Talluri, AntonioYanguas Leyes, JavierLukaski, HenryMusclesLocalized bioimpedanceMuscleReactanceMagnetic resonance imagingMúsculsÀrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdicaLocalized bioimpedance (L-BIA) measurements are an innovative method to non-invasively identify structural derangement of soft tissues, principally muscles, and fluid accumulation in response to traumatic injury. This review provides unique L-BIA data demonstrating significant relative differences between injured and contralateral non-injured regions of interest (ROI) associated with soft tissue injury. One key finding is the specific and sensitive role of reactance (Xc), measured at 50 kHz with a phase-sensitive BI instrument, to identify objective degrees of muscle injury, localized structural damage and fluid accretion, determined using magnetic resonance imaging. The predominant effect of Xc as an indicator of severity of muscle injury is highlighted in phase angle (PhA) measurements. Novel experimental models utilizing cooking-induced cell disruption, saline injection into meat specimens, and measurements of changing amounts of cells in a constant volume provide empirical evidence of the physiological correlates of series Xc as cells in water. Findings of strong associations of capacitance, computed from parallel Xc (XCP), with whole body counting of 40-potassium and resting metabolic rate support the hypothesis that parallel Xc is a biomarker of body cell mass. These observations provide a theoretical and practical basis for a significant role of Xc, and hence PhA, to identify objectively graded muscle injury and to reliably monitor progress of treatment and return of muscle function.Peer ReviewedSpringer Nature20232023-02-2720232023-04-27journal articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/386780https://dx.doi.org/10.1007/s11154-023-09790-9reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/3867802026-05-27T15:37:01Z
dc.title.none.fl_str_mv Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
title Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
spellingShingle Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
Nescolarde Selva, Lexa Digna|||0000-0001-6861-5106
Muscles
Localized bioimpedance
Muscle
Reactance
Magnetic resonance imaging
Músculs
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
title_short Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
title_full Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
title_fullStr Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
title_full_unstemmed Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
title_sort Phase angle in localized bioimpedance measurements to assess and monitor muscle injury
dc.creator.none.fl_str_mv Nescolarde Selva, Lexa Digna|||0000-0001-6861-5106
Talluri, Antonio
Yanguas Leyes, Javier
Lukaski, Henry
author Nescolarde Selva, Lexa Digna|||0000-0001-6861-5106
author_facet Nescolarde Selva, Lexa Digna|||0000-0001-6861-5106
Talluri, Antonio
Yanguas Leyes, Javier
Lukaski, Henry
author_role author
author2 Talluri, Antonio
Yanguas Leyes, Javier
Lukaski, Henry
author2_role author
author
author
dc.subject.none.fl_str_mv Muscles
Localized bioimpedance
Muscle
Reactance
Magnetic resonance imaging
Músculs
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
topic Muscles
Localized bioimpedance
Muscle
Reactance
Magnetic resonance imaging
Músculs
Àrees temàtiques de la UPC::Enginyeria biomèdica::Electrònica biomèdica
description Localized bioimpedance (L-BIA) measurements are an innovative method to non-invasively identify structural derangement of soft tissues, principally muscles, and fluid accumulation in response to traumatic injury. This review provides unique L-BIA data demonstrating significant relative differences between injured and contralateral non-injured regions of interest (ROI) associated with soft tissue injury. One key finding is the specific and sensitive role of reactance (Xc), measured at 50 kHz with a phase-sensitive BI instrument, to identify objective degrees of muscle injury, localized structural damage and fluid accretion, determined using magnetic resonance imaging. The predominant effect of Xc as an indicator of severity of muscle injury is highlighted in phase angle (PhA) measurements. Novel experimental models utilizing cooking-induced cell disruption, saline injection into meat specimens, and measurements of changing amounts of cells in a constant volume provide empirical evidence of the physiological correlates of series Xc as cells in water. Findings of strong associations of capacitance, computed from parallel Xc (XCP), with whole body counting of 40-potassium and resting metabolic rate support the hypothesis that parallel Xc is a biomarker of body cell mass. These observations provide a theoretical and practical basis for a significant role of Xc, and hence PhA, to identify objectively graded muscle injury and to reliably monitor progress of treatment and return of muscle function.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-02-27
2023
2023-04-27
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/386780
https://dx.doi.org/10.1007/s11154-023-09790-9
url https://hdl.handle.net/2117/386780
https://dx.doi.org/10.1007/s11154-023-09790-9
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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