Cognitive behavioral therapy for insomnia (CBT-i) in patients with fibromyalgia: a systematic review and meta-analysis

Purpose: We aimed to evaluate the effectiveness of CBT-i in patients with fibromyalgia in comparison with other non-pharmacological treatments. Methods: Randomized controlled trials assessing the effects of CBT-i in adults with fibromyalgia, published in English or Spanish, were eligible. Electronic...

Full description

Bibliographic Details
Authors: Climent Sanz, Carolina, Savulescu, Camelia, Martínez-Navarro, Oriol, Blanco-Blanco, Joan, Rubi Carnacea, Francesc Josep, García-Martínez, Ester, soler-gonzalez, jorge, Barallat Gimeno, Eva, Gea Sánchez, Montserrat
Format: article
Publication Date:2022
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:20.500.12328/4493
Online Access:http://hdl.handle.net/20.500.12328/4493
https://dx.doi.org/10.1080/09638288.2021.1954706
Access Level:Open access
Keyword:Fibromiàlgia
Insomni
Dormir
Mala qualitat del son
Teràpia cognitivo-conductual per a l'insomni
Revisió sistemàtica
Fibromialgia
Insomnio
Sueño
Mala calidad del sueño
Terapia cognitiva conductual para el insomnio
Revisión sistemática
Fibromyalgia
Insomnia
Sleep
Poor sleep quality
Cognitive behavioral therapy for insomnia
Systematic review
61
Description
Summary:Purpose: We aimed to evaluate the effectiveness of CBT-i in patients with fibromyalgia in comparison with other non-pharmacological treatments. Methods: Randomized controlled trials assessing the effects of CBT-i in adults with fibromyalgia, published in English or Spanish, were eligible. Electronic searches were performed using PubMed, Scopus, The Cochrane Library, WebOfKnowledge and Psicodoc databases in March 2021. The main outcome measures were sleep efficiency and sleep quality. Secondary outcomes included pain, depression, and anxiety. Results: Of 226 studies reviewed, five were included in the meta-analysis. CBT-i compared with non-pharmacological treatments showed no significant improvements in sleep efficiency (p = 0.05; standardized mean difference (SMD) [95% CI] 0.31 [−0.00 to 0.61]). CBT-i showed significant improvements in sleep quality (p = 0.009; SMD [95% CI] − 0.53 [−0.93 to −0.13]), pain (p = 0.002; SMD [95% CI] − 0.41 [−0.67 to −0.16]), anxiety (p = 0.001; SMD [95% CI] − 0.46 [−0.74 to 0.18]) and depression (p = 0.02; SMD [95% CI] − 0.33 [−0.61 to −0.05]), compared to non-pharmacological treatments. Effect sizes ranged from small to moderate. Conclusions: CBT-i was associated with a significant improvement in sleep quality, pain, anxiety, and depression, although these results are retrieved from very few studies with only very low to low quality evidence. Trial registration: The review protocol was registered with PROSPERO (Record ID = CRD42016030161).