CRISPR-Cas for fungal genome editing: a new tool for the management of plant diseases

[EN]Fungal pathogens are the main factors responsible for the most severe diseases affecting plants, leading to significant reduction in yield and crop quality and causing enormous economic losses worldwide. It is estimated that around 30% of the emerging diseases are caused by fungi thus requiring...

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Detalles Bibliográficos
Autores: Vicente Muñoz, Isabel, Sarrocco, Sabrina, Malfatti, Luca, Baroncelli, Riccardo, Vannacci, Giovanni
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/169918
Acceso en línea:http://hdl.handle.net/10366/169918
Access Level:acceso abierto
Palabra clave:genome editing
CRISPR-Cas9
filamentous fungi
biocontrol
plant diseases management
fungal pathogens
beneficial fungi
Fungi
Genetics
Plant Pathology
3108.05 Hongos
2409.02 Ingeniería Genética
3108 Fitopatología
hongos
patología de las plantas
genética
Descripción
Sumario:[EN]Fungal pathogens are the main factors responsible for the most severe diseases affecting plants, leading to significant reduction in yield and crop quality and causing enormous economic losses worldwide. It is estimated that around 30% of the emerging diseases are caused by fungi thus requiring new strategies to improve their management. Biological control approach, frequently referred to the use of non-pathogenic microbial antagonists or products derived from their metabolism, represents a valid and promising alternative under a more ecological perspective to reduce the activities and to control populations of target pathogens. However, although the use of antagonists belonging to species different from that of the pathogen has been successfully reported, the use of competitors belonging to the same species of the pathogen is not widespread. A biocontrol strategy based on competition for space and nutrients and/or the induction of plant defenses against virulent pathogens performed by attenuated or avirulent pathogens could, therefore, be considered a valid alternative.