Recent applications of high resolution mass spectrometry for the characterization of plant natural products

Recently, the high analytical power provided by the new HRMS instruments (working in the MS or MS/MS mode, stand alone or hyphenated with separation techniques) is making more feasible the characterization of plant secondary metabolites. In this regard, HRMS-based techniques are becoming the techniq...

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Detalles Bibliográficos
Autores: Álvarez-Rivera, Gerardo, Ballesteros-Vivas, Diego, Parada-Alfonso, Fabián, Ibáñez, Elena, Cifuentes, Alejandro
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/193709
Acceso en línea:http://hdl.handle.net/10261/193709
Access Level:acceso abierto
Palabra clave:Secondary metabolites
High resolution mass spectrometry
Hyphenated techniques
TOF
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spelling Recent applications of high resolution mass spectrometry for the characterization of plant natural productsÁlvarez-Rivera, GerardoBallesteros-Vivas, DiegoParada-Alfonso, FabiánIbáñez, ElenaCifuentes, AlejandroSecondary metabolitesHigh resolution mass spectrometryHyphenated techniquesTOFRecently, the high analytical power provided by the new HRMS instruments (working in the MS or MS/MS mode, stand alone or hyphenated with separation techniques) is making more feasible the characterization of plant secondary metabolites. In this regard, HRMS-based techniques are becoming the technique of choice, since they are capable of answering many questions regarding the analytical characterization of secondary metabolites, usually found in very complex matrices, including their structural elucidation and quantification in a very fast and sensitive way. In this manuscript we will provide a critical and updated revision of this topic covering the works published in the last 4 years (2015–2018), including the different configurations in which HRMS may be used (stand alone or hyphenated), the data treatment, the strategies for the identification of unknown metabolites, the current software for structure elucidation, as well as the last trends and future outlooks in this hot area of research.This research was supported by COOPA20145, project from CSIC (Programa de Cooperación Científica para el Desarrollo “i-COOP+"). G.A.-R. would like to acknowledge the Ministry of Economy and Competitiveness for a “Juan de la Cierva” postdoctoral grant. The authors also thank the support from the AGL2017-89417-R project.Peer reviewedElsevierMinisterio de Ciencia, Innovación y Universidades (España)Agencia Estatal de Investigación (España)Consejo Superior de Investigaciones Científicas (España)Ministerio de Economía y Competitividad (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201920192019info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/193709reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/AGL2017-89417-RAGL2017-89417-R/AEI/10.13039/501100011033https://doi.org/10.1016/j.trac.2019.01.002Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1937092026-05-22T06:33:51Z
dc.title.none.fl_str_mv Recent applications of high resolution mass spectrometry for the characterization of plant natural products
title Recent applications of high resolution mass spectrometry for the characterization of plant natural products
spellingShingle Recent applications of high resolution mass spectrometry for the characterization of plant natural products
Álvarez-Rivera, Gerardo
Secondary metabolites
High resolution mass spectrometry
Hyphenated techniques
TOF
title_short Recent applications of high resolution mass spectrometry for the characterization of plant natural products
title_full Recent applications of high resolution mass spectrometry for the characterization of plant natural products
title_fullStr Recent applications of high resolution mass spectrometry for the characterization of plant natural products
title_full_unstemmed Recent applications of high resolution mass spectrometry for the characterization of plant natural products
title_sort Recent applications of high resolution mass spectrometry for the characterization of plant natural products
dc.creator.none.fl_str_mv Álvarez-Rivera, Gerardo
Ballesteros-Vivas, Diego
Parada-Alfonso, Fabián
Ibáñez, Elena
Cifuentes, Alejandro
author Álvarez-Rivera, Gerardo
author_facet Álvarez-Rivera, Gerardo
Ballesteros-Vivas, Diego
Parada-Alfonso, Fabián
Ibáñez, Elena
Cifuentes, Alejandro
author_role author
author2 Ballesteros-Vivas, Diego
Parada-Alfonso, Fabián
Ibáñez, Elena
Cifuentes, Alejandro
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Agencia Estatal de Investigación (España)
Consejo Superior de Investigaciones Científicas (España)
Ministerio de Economía y Competitividad (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Secondary metabolites
High resolution mass spectrometry
Hyphenated techniques
TOF
topic Secondary metabolites
High resolution mass spectrometry
Hyphenated techniques
TOF
description Recently, the high analytical power provided by the new HRMS instruments (working in the MS or MS/MS mode, stand alone or hyphenated with separation techniques) is making more feasible the characterization of plant secondary metabolites. In this regard, HRMS-based techniques are becoming the technique of choice, since they are capable of answering many questions regarding the analytical characterization of secondary metabolites, usually found in very complex matrices, including their structural elucidation and quantification in a very fast and sensitive way. In this manuscript we will provide a critical and updated revision of this topic covering the works published in the last 4 years (2015–2018), including the different configurations in which HRMS may be used (stand alone or hyphenated), the data treatment, the strategies for the identification of unknown metabolites, the current software for structure elucidation, as well as the last trends and future outlooks in this hot area of research.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019
2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/193709
url http://hdl.handle.net/10261/193709
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/AGL2017-89417-R
AGL2017-89417-R/AEI/10.13039/501100011033
https://doi.org/10.1016/j.trac.2019.01.002
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
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