Management of enzyme diversity in high-performance cellulolytic cocktails

[Background] Modern biorefineries require enzymatic cocktails of improved efficiency to generate fermentable sugars from lignocellulosic biomass. Cellulolytic fungi, among other microorganisms, have demonstrated the highest potential in terms of enzymatic productivity, complexity and efficiency. On...

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Bibliographic Details
Authors: Reyes-Sosa, Francisco M., López Morales, Macarena, Platero Gómez, Ana Isabel, Valbuena Crespo, Noelia, Sánchez Zamorano, Laura, Rocha-Martín, Javier, Molina-Heredia, Fernando P., Diéz-García, Bruno
Format: article
Status:Published version
Publication Date:2017
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/151975
Online Access:http://hdl.handle.net/10261/151975
Access Level:Open access
Keyword:Enzymatic hydrolysis
Cellulolytic cocktail improvement
Lignocellulosic biomass
Bioethanol
Description
Summary:[Background] Modern biorefineries require enzymatic cocktails of improved efficiency to generate fermentable sugars from lignocellulosic biomass. Cellulolytic fungi, among other microorganisms, have demonstrated the highest potential in terms of enzymatic productivity, complexity and efficiency. On the other hand, under cellulolytic-inducing conditions, they often produce a considerable diversity of carbohydrate-active enzymes which allow them to adapt to changing environmental conditions. However, industrial conditions are fixed and adjusted to the optimum of the whole cocktail, resulting in underperformance of individual enzymes.

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