Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study

Background: Barrett’s esophagus (BE) is an acquired disease defined by the presence of intestinal metaplasia with goblet cells in the distal esophagus. The prevalence of BE has increased dramati cally over the last years. Aims: The primary aims of the study were to analyze the char acteristics of BE...

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Autores: Arroyo Martínez, Quetzalihuitl, Rodríguez Téllez, Manuel José, García Escudero, Antonio, Brugal Medina, Javier, González Cámpora, Ricardo, Caunedo Álvarez, Ángel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/158835
Acceso en línea:https://hdl.handle.net/11441/158835
https://doi.org/10.17235/reed.2016.4229/2016
Access Level:acceso abierto
Palabra clave:Esophageal adenocarcinoma
Barrett’s esophagus
Metaplasia. Dysplasia
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spelling Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric studyArroyo Martínez, QuetzalihuitlRodríguez Téllez, Manuel JoséGarcía Escudero, AntonioBrugal Medina, JavierGonzález Cámpora, RicardoCaunedo Álvarez, ÁngelEsophageal adenocarcinomaBarrett’s esophagusMetaplasia. DysplasiaBackground: Barrett’s esophagus (BE) is an acquired disease defined by the presence of intestinal metaplasia with goblet cells in the distal esophagus. The prevalence of BE has increased dramati cally over the last years. Aims: The primary aims of the study were to analyze the char acteristics of BE and esophageal adenocarcinoma (EAC) in a Span ish health district during a follow-up period. Methodology: Sociodemographic factors, alcohol consump tion and cigarette smoking were analyzed. We also studied the histological behavior and cause of death in each group. Results: In the present study 430 patients were included, 338 with BE and 92 with EAC. Incidence rates have risen from 2.25 and 1.25 per 100,000 inhabitants in 1996 to 6.5 and 4.75 per 100,000 in 2011, respectively. In the EAC group, male gender, age and alcohol consumption were higher in comparison to the BE group, and the overall survival was 23 months. In the BE group, the main causes of death were non-esophageal cancer and cardio vascular disease. Conclusions: The incidence and prevalence rates of AEC and BE have risen over the past years. Risk factors for these conditions were male gender, age and alcohol consumption. Long BE (> 3 cm) is involved in dysplasia progression. AEC diagnosis mainly occurs after neoplasia is detected and, in a few cases, due to a previous BE. Cardiovascular diseases and non-esophageal cancers have been found to be the main cause of death in BE patients.Aran Ediciones S.A.Medicina2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/158835https://doi.org/10.17235/reed.2016.4229/2016reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésRevista Española de Enfermedades Digestivas, 108 (10), 609-616.https://www.reed.es/epidemiology-of-barrett%e2%80%99s-esophagus-and-esophageal-adenocarcinoma-in-spain-a-unicentric-study1098info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1588352026-06-17T12:51:07Z
dc.title.none.fl_str_mv Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
title Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
spellingShingle Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
Arroyo Martínez, Quetzalihuitl
Esophageal adenocarcinoma
Barrett’s esophagus
Metaplasia. Dysplasia
title_short Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
title_full Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
title_fullStr Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
title_full_unstemmed Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
title_sort Epidemiology of Barrett’s esophagus and esophageal adenocarcinoma in Spain. A unicentric study
dc.creator.none.fl_str_mv Arroyo Martínez, Quetzalihuitl
Rodríguez Téllez, Manuel José
García Escudero, Antonio
Brugal Medina, Javier
González Cámpora, Ricardo
Caunedo Álvarez, Ángel
author Arroyo Martínez, Quetzalihuitl
author_facet Arroyo Martínez, Quetzalihuitl
Rodríguez Téllez, Manuel José
García Escudero, Antonio
Brugal Medina, Javier
González Cámpora, Ricardo
Caunedo Álvarez, Ángel
author_role author
author2 Rodríguez Téllez, Manuel José
García Escudero, Antonio
Brugal Medina, Javier
González Cámpora, Ricardo
Caunedo Álvarez, Ángel
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Medicina
dc.subject.none.fl_str_mv Esophageal adenocarcinoma
Barrett’s esophagus
Metaplasia. Dysplasia
topic Esophageal adenocarcinoma
Barrett’s esophagus
Metaplasia. Dysplasia
description Background: Barrett’s esophagus (BE) is an acquired disease defined by the presence of intestinal metaplasia with goblet cells in the distal esophagus. The prevalence of BE has increased dramati cally over the last years. Aims: The primary aims of the study were to analyze the char acteristics of BE and esophageal adenocarcinoma (EAC) in a Span ish health district during a follow-up period. Methodology: Sociodemographic factors, alcohol consump tion and cigarette smoking were analyzed. We also studied the histological behavior and cause of death in each group. Results: In the present study 430 patients were included, 338 with BE and 92 with EAC. Incidence rates have risen from 2.25 and 1.25 per 100,000 inhabitants in 1996 to 6.5 and 4.75 per 100,000 in 2011, respectively. In the EAC group, male gender, age and alcohol consumption were higher in comparison to the BE group, and the overall survival was 23 months. In the BE group, the main causes of death were non-esophageal cancer and cardio vascular disease. Conclusions: The incidence and prevalence rates of AEC and BE have risen over the past years. Risk factors for these conditions were male gender, age and alcohol consumption. Long BE (> 3 cm) is involved in dysplasia progression. AEC diagnosis mainly occurs after neoplasia is detected and, in a few cases, due to a previous BE. Cardiovascular diseases and non-esophageal cancers have been found to be the main cause of death in BE patients.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/158835
https://doi.org/10.17235/reed.2016.4229/2016
url https://hdl.handle.net/11441/158835
https://doi.org/10.17235/reed.2016.4229/2016
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Revista Española de Enfermedades Digestivas, 108 (10), 609-616.
https://www.reed.es/epidemiology-of-barrett%e2%80%99s-esophagus-and-esophageal-adenocarcinoma-in-spain-a-unicentric-study1098
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Aran Ediciones S.A.
publisher.none.fl_str_mv Aran Ediciones S.A.
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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