Recent advances in the synthesis of azaphenalene alkaloids

Azaphenalene alkaloids are biosynthesised and segregated by diverse insects of the Coccinellidae family (ladybirds) and are believed to play an important role in the defensive mechanism against their natural predators. The particular unique framework of these alkaloids, along with their potential in...

Descripción completa

Detalles Bibliográficos
Autores: Alujas Burgos, Sílvia, Bayón, Pau|||0000-0002-3064-8866, Figueredo Galimany, Marta|||0000-0002-8278-7534
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:195986
Acceso en línea:https://ddd.uab.cat/record/195986
https://dx.doi.org/urn:doi:10.1039/c8ob01443d
Access Level:acceso abierto
Descripción
Sumario:Azaphenalene alkaloids are biosynthesised and segregated by diverse insects of the Coccinellidae family (ladybirds) and are believed to play an important role in the defensive mechanism against their natural predators. The particular unique framework of these alkaloids, along with their potential in the field of biological pest control, has led to several research groups developing synthetic sequences to prepare these compounds. The main purpose of the present review is to provide an update of the more recent synthetic progress towards these alkaloids, including the pioneering enantioselective approaches to chiral congeners.