GradCAM as an explicability method to evaluate the performance of deep learning models in classifying pediatric arteriovenous malformations (AVM) in arterial spin labeling sequences (ASL)

PurposeThe study investigates the usefulness of Convolutional Neural Networks (CNNs) in accurately detecting arteriovenous malformations in pediatric medical imaging, particularly using arterial spin labeling sequences. It also aims to offer diagnostic explanations comparable to expert analysis.Meth...

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Detalles Bibliográficos
Autores: Romagosa, J, Mata, C, Benítez, R, Valls-Esteve, A, Bernaus, S, Ibnoulkhatib, M, Stephan-Otto, C, Munuera, J
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p20291
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=20291
Access Level:acceso abierto
Palabra clave:Explainable AI
Grad-CAM
Deep learning
CNN
Arteriovenous malformations
Arterial spin labeling
Magnetic resonance imaging
Medical imaging
Descripción
Sumario:PurposeThe study investigates the usefulness of Convolutional Neural Networks (CNNs) in accurately detecting arteriovenous malformations in pediatric medical imaging, particularly using arterial spin labeling sequences. It also aims to offer diagnostic explanations comparable to expert analysis.MethodsThe research analyzed three different CNN architectures to determine their performance in detecting arteriovenous malformations. The study focused on evaluating the relationship between model complexity and performance increase, using data to assess the accuracy and diagnostic usefulness of each model.ResultsThe findings indicated a nonlinear link between model complexity and performance. Sur- prisingly, more complex models frequently produced poor results and diagnostically useless answers. The simplest CNN models achieved the highest accuracy rate (90%), demonstrating the effectiveness of minimal complexity in model construction. Heat maps showed a strong association with the real locations of irregularities, indicating that the models were interpretable.ConclusionThe study highlights the usefulness of CNNs in medical diagnostics, emphasizing the importance of model simplicity and interpretability in clinical applications. It suggests a need for balancing technical sophistication with clinical value and presents options for future research into refining CNN structures for increased diagnostic precision in various medical imaging modalities.