Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design

Introduction and objectives: The optimal time to perform a diagnostic coronary angiography in patients admitted due to non- ST-segment elevation acute coronary syndrome (NSTEACS) and start pretreatment with dual antiplatelet therapy is controversial. Our study aims to identify the current diagnostic...

Descripción completa

Detalles Bibliográficos
Autores: Díez-Delhoyo, F, Díez-Villanueva, P, Lluva, MTL, Abellas, M, Amat-Santos, I, Bazal-Chacón, P, Carrasquer, A, Corbí, M, Escribano, D, Elorriaga, A, García-Blas, S, Giralt-Borrell, T, Jurado-Román, A, Llaó, I, Matute-Blanco, L, Negreira-Caamaño, M, Pérez-Cebey, L, Rivera-López, R, Robles-Gamboa, C, Salinas, P, Mezcúa, FJT, Olavarri-Miguel, I, Vaquero-Luna, J, Cepas-Guillén, P
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p18952
Acceso en línea:https://incliva.portalinvestigacion.com/publicaciones/18952
Access Level:acceso abierto
Palabra clave:Sindrome coronario agudo. Infarto agudo de miocardio. Sindrome coronario agudo sin elevacion del segmento ST. Doble
antiagregacion plaquetaria. Pretratamiento. Coronariografia precoz. Guia ESC. Diabetes mellitus. Hemorragia. Revascularizacion.
id ES_ef2ee5efcbd806daceaf821497553def
oai_identifier_str oai:incliva.fundanetsuite.com:p18952
network_acronym_str ES
network_name_str España
repository_id_str
spelling Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial designDíez-Delhoyo, FDíez-Villanueva, PLluva, MTLAbellas, MAmat-Santos, IBazal-Chacón, PCarrasquer, ACorbí, MEscribano, DElorriaga, AGarcía-Blas, SGiralt-Borrell, TJurado-Román, ALlaó, IMatute-Blanco, LNegreira-Caamaño, MPérez-Cebey, LRivera-López, RRobles-Gamboa, CSalinas, PMezcúa, FJTOlavarri-Miguel, IVaquero-Luna, JCepas-Guillén, PSindrome coronario agudo. Infarto agudo de miocardio. Sindrome coronario agudo sin elevacion del segmento ST. Dobleantiagregacion plaquetaria. Pretratamiento. Coronariografia precoz. Guia ESC. Diabetes mellitus. Hemorragia. Revascularizacion.Introduction and objectives: The optimal time to perform a diagnostic coronary angiography in patients admitted due to non- ST-segment elevation acute coronary syndrome (NSTEACS) and start pretreatment with dual antiplatelet therapy is controversial. Our study aims to identify the current diagnostic and therapeutic approach, and clinical progression of patients with NSTEACS in our country. Methods: The IMPACT-TIMING-GO trial (Impact of time of intervention in patients with myocardial infarction with non-ST segment elevation. Management and outcomes) is a national, observational, prospective, and multicenter registry that will include consecutive patients from 24 Spanish centers with a clinical diagnosis of NSTEACS treated with diagnostic coronary angiography and with present unstable or causal atherosclerotic coronary artery disease. The study primary endpoint is to assess the level of compliance to clinical practice guidelines in patients admitted due to NSTEACS undergoing coronary angiography in Spain, describe the use of antithrombotic treatment prior to cardiac catheterization, and register the time elapsed until it is performed. Major adverse cardiovascular events will also be described like all-cause mortality, non-fatal myocardial infarction and non-fatal stroke, and the rate of major bleeding according to the BARC (Bleeding Academic Research Consortium) scale at 1- and 3-year follow-up. Results: This study will provide more information on the impact of different early management strategies in patients admitted with NSTEACS in Spain, and the degree of implementation of current recommendations into the routine clinical practice. It will also provide information on these patients' baseline and clinical characteristics. Conclusions: This is the first prospective study conducted in Spain that will be reporting on the early therapeutic strategies-both pharmacological and interventional-implemented in our country in patients with NSTEACS after the publication of the 2020 European guidelines, and on the clinical short- and long-term outcomes of these patients.PERMANYER PUBL2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://incliva.portalinvestigacion.com/publicaciones/18952REC-Interventional CardiologyISSN: 26047306ISSNe: 26047276reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVAinstname:INCLIVAInglésinfo:eu-repo/semantics/openAccessoai:incliva.fundanetsuite.com:p189522026-06-07T16:35:31Z
dc.title.none.fl_str_mv Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
title Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
spellingShingle Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
Díez-Delhoyo, F
Sindrome coronario agudo. Infarto agudo de miocardio. Sindrome coronario agudo sin elevacion del segmento ST. Doble
antiagregacion plaquetaria. Pretratamiento. Coronariografia precoz. Guia ESC. Diabetes mellitus. Hemorragia. Revascularizacion.
title_short Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
title_full Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
title_fullStr Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
title_full_unstemmed Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
title_sort Impact of time of intervention in patients with NSTEMI. The IMPACT-TIMING-GO trial design
dc.creator.none.fl_str_mv Díez-Delhoyo, F
Díez-Villanueva, P
Lluva, MTL
Abellas, M
Amat-Santos, I
Bazal-Chacón, P
Carrasquer, A
Corbí, M
Escribano, D
Elorriaga, A
García-Blas, S
Giralt-Borrell, T
Jurado-Román, A
Llaó, I
Matute-Blanco, L
Negreira-Caamaño, M
Pérez-Cebey, L
Rivera-López, R
Robles-Gamboa, C
Salinas, P
Mezcúa, FJT
Olavarri-Miguel, I
Vaquero-Luna, J
Cepas-Guillén, P
author Díez-Delhoyo, F
author_facet Díez-Delhoyo, F
Díez-Villanueva, P
Lluva, MTL
Abellas, M
Amat-Santos, I
Bazal-Chacón, P
Carrasquer, A
Corbí, M
Escribano, D
Elorriaga, A
García-Blas, S
Giralt-Borrell, T
Jurado-Román, A
Llaó, I
Matute-Blanco, L
Negreira-Caamaño, M
Pérez-Cebey, L
Rivera-López, R
Robles-Gamboa, C
Salinas, P
Mezcúa, FJT
Olavarri-Miguel, I
Vaquero-Luna, J
Cepas-Guillén, P
author_role author
author2 Díez-Villanueva, P
Lluva, MTL
Abellas, M
Amat-Santos, I
Bazal-Chacón, P
Carrasquer, A
Corbí, M
Escribano, D
Elorriaga, A
García-Blas, S
Giralt-Borrell, T
Jurado-Román, A
Llaó, I
Matute-Blanco, L
Negreira-Caamaño, M
Pérez-Cebey, L
Rivera-López, R
Robles-Gamboa, C
Salinas, P
Mezcúa, FJT
Olavarri-Miguel, I
Vaquero-Luna, J
Cepas-Guillén, P
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Sindrome coronario agudo. Infarto agudo de miocardio. Sindrome coronario agudo sin elevacion del segmento ST. Doble
antiagregacion plaquetaria. Pretratamiento. Coronariografia precoz. Guia ESC. Diabetes mellitus. Hemorragia. Revascularizacion.
topic Sindrome coronario agudo. Infarto agudo de miocardio. Sindrome coronario agudo sin elevacion del segmento ST. Doble
antiagregacion plaquetaria. Pretratamiento. Coronariografia precoz. Guia ESC. Diabetes mellitus. Hemorragia. Revascularizacion.
description Introduction and objectives: The optimal time to perform a diagnostic coronary angiography in patients admitted due to non- ST-segment elevation acute coronary syndrome (NSTEACS) and start pretreatment with dual antiplatelet therapy is controversial. Our study aims to identify the current diagnostic and therapeutic approach, and clinical progression of patients with NSTEACS in our country. Methods: The IMPACT-TIMING-GO trial (Impact of time of intervention in patients with myocardial infarction with non-ST segment elevation. Management and outcomes) is a national, observational, prospective, and multicenter registry that will include consecutive patients from 24 Spanish centers with a clinical diagnosis of NSTEACS treated with diagnostic coronary angiography and with present unstable or causal atherosclerotic coronary artery disease. The study primary endpoint is to assess the level of compliance to clinical practice guidelines in patients admitted due to NSTEACS undergoing coronary angiography in Spain, describe the use of antithrombotic treatment prior to cardiac catheterization, and register the time elapsed until it is performed. Major adverse cardiovascular events will also be described like all-cause mortality, non-fatal myocardial infarction and non-fatal stroke, and the rate of major bleeding according to the BARC (Bleeding Academic Research Consortium) scale at 1- and 3-year follow-up. Results: This study will provide more information on the impact of different early management strategies in patients admitted with NSTEACS in Spain, and the degree of implementation of current recommendations into the routine clinical practice. It will also provide information on these patients' baseline and clinical characteristics. Conclusions: This is the first prospective study conducted in Spain that will be reporting on the early therapeutic strategies-both pharmacological and interventional-implemented in our country in patients with NSTEACS after the publication of the 2020 European guidelines, and on the clinical short- and long-term outcomes of these patients.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://incliva.portalinvestigacion.com/publicaciones/18952
url https://incliva.portalinvestigacion.com/publicaciones/18952
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv PERMANYER PUBL
publisher.none.fl_str_mv PERMANYER PUBL
dc.source.none.fl_str_mv REC-Interventional Cardiology
ISSN: 26047306
ISSNe: 26047276
reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname:INCLIVA
instname_str INCLIVA
reponame_str r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
collection r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869423839777128448
score 15,81155

Similares en LA Referencia