Prevalence of thrombotic complications in children with SARS-CoV-2

Knowledge of thrombosis in children with SARS-CoV-2 is scarce. In this multicentre national cohort of children with SARS-CoV-2 involving 49 hospitals, 4 patients out of 537 infected children developed a thrombotic complication (prevalence of 0.7% (95% CI: 0.2% to 1.9%) out of the global cohort and 1...

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Detalles Bibliográficos
Autores: Aguilera Alonso, David, Murias, Sara, Martínez de Azagra Garde, Amelia, Soriano Arandes, Antoni, Pareja, Marta, Otheo, Enrique, Moraleda, Cinta, Tagarro García, Alfredo, Calvo, Cristina, EPICO-AEP Working Group
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/11438
Acceso en línea:http://hdl.handle.net/11268/11438
Access Level:acceso abierto
Palabra clave:Trombosis
COVID-19
Niño
Epidemiología
Virus
Efectos fisiológicos
Descripción
Sumario:Knowledge of thrombosis in children with SARS-CoV-2 is scarce. In this multicentre national cohort of children with SARS-CoV-2 involving 49 hospitals, 4 patients out of 537 infected children developed a thrombotic complication (prevalence of 0.7% (95% CI: 0.2% to 1.9%) out of the global cohort and 1.1% (95% CI: 0.3% to 2.8%) out of the hospitalised patients). We describe their characteristics and review other published paediatric cases. Three out of the four patients were adolescent girls, and only two cases had significant thrombotic risk factors. In this paediatric cohort, D-dimer value was not specific enough to predict thrombotic complications. Adolescence and previous thrombotic risk factors may be considered when initiating anticoagulant prophylaxis on children with SARS-CoV-2 disease (COVID-19).