Dataset of Oddball Paradigm experiment in the Auditory Cortex and the effect of acetylcholine

[EN]This work presents three open datasets featuring various levels of processing, containing neural recordings from the auditory cortex of rats. These recordings were obtained during experiments using the auditory oddball paradigm before, during and after the local microiontophoretic application of...

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Detalles Bibliográficos
Autores: Vázquez-Borsetti, Pablo, Lao Rodríguez, Ana Belén, Malmierca, Manuel S., Pérez González, David
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/169921
Acceso en línea:http://hdl.handle.net/10366/169921
Access Level:acceso abierto
Palabra clave:acetylcholine
animal
auditory cortex
auditory stimulation
drug effect
hearing
physiology
rat
2490 Neurociencias
Descripción
Sumario:[EN]This work presents three open datasets featuring various levels of processing, containing neural recordings from the auditory cortex of rats. These recordings were obtained during experiments using the auditory oddball paradigm before, during and after the local microiontophoretic application of acetylcholine. The primary objective of these datasets is to investigate how the brain processes predictable versus unexpected auditory stimuli, and the role of cholinergic inputs during such processing. The data include multi-unit recordings of neuronal activity during the presentation of standard and deviant tones, classified by stimulus type and cortical sub-region. These resources enable quantitative investigations of deviance detection, stimulus-specific adaptation, cholinergic modulation and predictive-coding mechanisms at multiple temporal scales.