Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles

This article belongs to the Special Issue Advances in Phosphate Materials: Structural, Technological and Biomedical Applications.

Detalles Bibliográficos
Autores: García, Inés, Trobajo, Camino, Amghouz, Zakariae, Adawy, Alaa
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/259148
Acceso en línea:http://hdl.handle.net/10261/259148
Access Level:acceso abierto
Palabra clave:Inorganic layered nanomaterials
Bone cement
Antimicrobial activity
Cytocompatibility
Titanium phosphate
Silver nanoparticles
Zirconium phosphate
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spelling Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticlesGarcía, InésTrobajo, CaminoAmghouz, ZakariaeAdawy, AlaaInorganic layered nanomaterialsBone cementAntimicrobial activityCytocompatibilityTitanium phosphateSilver nanoparticlesZirconium phosphateThis article belongs to the Special Issue Advances in Phosphate Materials: Structural, Technological and Biomedical Applications.There is an increasing demand on synthesizing pharmaceuticals and biomaterials that possess antimicrobial and/or antiviral activities. In this respective silver nanoparticles are known for their excellent antimicrobial activity. Nevertheless, their uncontrolled release in a biological medium can induce a cytotoxic effect. For this, we explored the use of nanolayered metal phosphates based on titanium and zirconium as materials that can be enriched with silver nanoparticles. Employing the hydrothermal route, crystalline α-phases of zirconium and titanium phosphates (α-ZrP, α-TiP) were synthesized and there after surface-enriched with silver nanoparticles. The structural assessment confirmed the stability of the structures and their sizes are in the nanoscale at least in one dimension. The cytocompatibility assays confirmed the biocompatibility of the pristine phases and the antimicrobial assay confirmed that both silver-enriched nanolayered structures maintain an antibacterial effect at reasonably low concentrations.This research was funded by MINECO, grant number MAT2016-78155-C2-1-R and by the Government of the Principality of Asturias, grant number GRUPIN-IDI/2018/170.Peer reviewedMultidisciplinary Digital Publishing InstituteMinisterio de Economía y Competitividad (España)Principado de AsturiasConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202220222021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/259148reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2016-78155-C2-1-Rhttps://doi.org/10.3390/ma14061481Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2591482026-05-22T06:33:51Z
dc.title.none.fl_str_mv Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
title Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
spellingShingle Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
García, Inés
Inorganic layered nanomaterials
Bone cement
Antimicrobial activity
Cytocompatibility
Titanium phosphate
Silver nanoparticles
Zirconium phosphate
title_short Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
title_full Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
title_fullStr Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
title_full_unstemmed Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
title_sort Nanolayered metal phosphates as biocompatible reservoirs for antimicrobial silver nanoparticles
dc.creator.none.fl_str_mv García, Inés
Trobajo, Camino
Amghouz, Zakariae
Adawy, Alaa
author García, Inés
author_facet García, Inés
Trobajo, Camino
Amghouz, Zakariae
Adawy, Alaa
author_role author
author2 Trobajo, Camino
Amghouz, Zakariae
Adawy, Alaa
author2_role author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
Principado de Asturias
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Inorganic layered nanomaterials
Bone cement
Antimicrobial activity
Cytocompatibility
Titanium phosphate
Silver nanoparticles
Zirconium phosphate
topic Inorganic layered nanomaterials
Bone cement
Antimicrobial activity
Cytocompatibility
Titanium phosphate
Silver nanoparticles
Zirconium phosphate
description This article belongs to the Special Issue Advances in Phosphate Materials: Structural, Technological and Biomedical Applications.
publishDate 2021
dc.date.none.fl_str_mv 2021
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/259148
url http://hdl.handle.net/10261/259148
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2016-78155-C2-1-R
https://doi.org/10.3390/ma14061481
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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