SEOM–GEMCAD–TTD clinical guidelines for anal cancer (2025)

Anal cancer is rare but increasingly common, currently accounting for 2% of all digestive neoplasms. Some 50% of anal cancers are diagnosed at the localized stage, 29% as locoregional disease, and 12% as metastatic disease. When clinical suspicion of anal cancer exists, histological confirmation, co...

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Detalles Bibliográficos
Autores: Guillot-Morales, Monica, Montes, Ana Fernández, Fernández-Plana, Julen, Cañete, Ismael Ghanem, Raga, Mireia Gil, Jiménez-Castro, Jerónimo, Martel, Ignacio Juez, Santasusana, Joan Maurel, Marqués, Eduardo Polo, Gómez-España, Ma Auxiliadora
Tipo de recurso: artículo
Fecha de publicación:2026
País:España
Institución:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/26652
Acceso en línea:https://hdl.handle.net/20.500.13003/26652
Access Level:acceso abierto
Palabra clave:Anal cancer
Chemoradiotherapy
HPV
Multidisciplinary
Treatment
Descripción
Sumario:Anal cancer is rare but increasingly common, currently accounting for 2% of all digestive neoplasms. Some 50% of anal cancers are diagnosed at the localized stage, 29% as locoregional disease, and 12% as metastatic disease. When clinical suspicion of anal cancer exists, histological confirmation, correct local staging with MRI and distant staging with thoraco-abdominal CT, and management by a multidisciplinary team are mandatory. Chemoradiotherapy with 5-FU and mitomycin C (MMC) is the standard of care for early and locally advanced disease, while combination chemotherapy with a platinum-containing compound and taxanes is the treatment of choice for metastatic disease.