Effect of ethanol on the cerebellar cortex of the chick embryo

The effect of ethanol on the cerebellar cortex of chick embryos was studied in semi-thin sections of material prepared for electron microscopy. The embryos were injected with ethanol on the 3rd or 6th day of incubation and observed until days 13, 15, 17 and 21 of development. A decrease was seen in...

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Detalles Bibliográficos
Autores: Quesada Ruiz, Adela, Prada Elena, Francisco Andrés, Espinar García, Auxiliadora, Genis Gálvez, José María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1990
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/59864
Acceso en línea:http://hdl.handle.net/11441/59864
Access Level:acceso abierto
Palabra clave:Ethanol
Cerebellum
Granule cells
Chick
Descripción
Sumario:The effect of ethanol on the cerebellar cortex of chick embryos was studied in semi-thin sections of material prepared for electron microscopy. The embryos were injected with ethanol on the 3rd or 6th day of incubation and observed until days 13, 15, 17 and 21 of development. A decrease was seen in the number of germinal cells generated, together with defects in neuronal migration and the existence of a lower quantity of cells due to a generalised process of cell death. At the same time, a progressive neuronal degeneration was observed until the 15th day of incubation, the tissue recovering progressively on days 17 and 21. On the other hand, the embryos treated with ethanol on the 3rd day were less affected than those injected on the 6th day.