Risk factors for hospital readmission following complicated urinary tract infection

Hospital readmissions following severe infections are a major economic burden on the health care system and have a negative influence on patients' quality of life. Understanding the risk factors for readmission, particularly the extent to which they could be prevented, is of a great importance....

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Autores: Babich, Tanya, Eliakim-Raz, Noa, Turjeman, Adi, Pujol Rojo, Miquel, Carratalà, Jordi, Shaw Perujo, Evelyn, Gomila Grange, Aina, Vuong, Cuong, Addy, Ibironke, Wiegand, Irith, Grier, Sally, MacGowan, Alasdair, Vank, Christiane, van den Heuvel, Leonard, Leibovici, Leonard
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/176914
Acesso em linha:https://hdl.handle.net/2445/176914
Access Level:acceso abierto
Palavra-chave:Infeccions del tracte urinari
Factors de risc en les malalties
Risk factors in diseases
Urinary tract infections
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spelling Risk factors for hospital readmission following complicated urinary tract infectionBabich, TanyaEliakim-Raz, NoaTurjeman, AdiPujol Rojo, MiquelCarratalà, JordiShaw Perujo, EvelynGomila Grange, AinaVuong, CuongAddy, IbironkeWiegand, IrithGrier, SallyMacGowan, AlasdairVank, Christianevan den Heuvel, LeonardLeibovici, LeonardInfeccions del tracte urinariFactors de risc en les malaltiesRisk factors in diseasesUrinary tract infectionsHospital readmissions following severe infections are a major economic burden on the health care system and have a negative influence on patients' quality of life. Understanding the risk factors for readmission, particularly the extent to which they could be prevented, is of a great importance. In this study we evaluated potentially preventable risk factors for 60-day readmission in patients surviving hospitalization for complicated urinary tract infection (cUTI). This was a multinational, multicentre retrospective cohort study conducted in Europe and the Middle East. Our cohort included survivors of hospitalization due to cUTI during the years 2013-2014. The primary outcome was 60-day readmission following index hospitalization. Patient characteristics that could have influenced readmission: demographics, infection presentation and management, microbiological and clinical data; were collected via computerized medical records from infection onset up to 60 days after hospital discharge. Overall, 742 patients were included. The cohort median age was 68 years (interquartile range, (IQR) 55-80) and 43.3% (321/742) of patients were males. The all-cause 60-day readmission rate was 20.1% (149/742) and more than half were readmitted for infection [57.1%, (80/140)]. Recurrent cUTI was the most frequent cause for readmission [46.4% (65/140)]. Statistically significant risk factors associated with 60-day readmission in multivariable analysis were: older age (odds ratio (OR) 1.02 for an one-year increment, confidence interval (CI) 1.005-1.03), diabetes mellitus (OR 1.63, 95% CI 1.04-2.55), cancer (OR 1.7, 95% CI 1.05-2.77), previous urinary tract infection (UTI) in the last year (OR 1.8, 95% CI: 1.14-2.83), insertion of an indwelling bladder catheter (OR 1.62, 95% CI 1.07-2.45) and insertion of percutaneous nephrostomy (OR 3.68, 95% CI 1.67-8.13). In conclusion, patients surviving hospitalization for cUTI are frequently re-hospitalized, mostly for recurrent urinary infections associated with a medical condition that necessitated urinary interventions. Interventions to avoid re-admissions should target these patients.Springer Nature2021202120212021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion7 p.application/pdfapplication/pdfhttps://hdl.handle.net/2445/176914Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1038/s41598-021-86246-7Scientific Reports, 2021, vol. 11https://doi.org/10.1038/s41598-021-86246-7cc by (c) Babich et al., 2021http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1769142026-05-29T05:05:01Z
dc.title.none.fl_str_mv Risk factors for hospital readmission following complicated urinary tract infection
title Risk factors for hospital readmission following complicated urinary tract infection
spellingShingle Risk factors for hospital readmission following complicated urinary tract infection
Babich, Tanya
Infeccions del tracte urinari
Factors de risc en les malalties
Risk factors in diseases
Urinary tract infections
title_short Risk factors for hospital readmission following complicated urinary tract infection
title_full Risk factors for hospital readmission following complicated urinary tract infection
title_fullStr Risk factors for hospital readmission following complicated urinary tract infection
title_full_unstemmed Risk factors for hospital readmission following complicated urinary tract infection
title_sort Risk factors for hospital readmission following complicated urinary tract infection
dc.creator.none.fl_str_mv Babich, Tanya
Eliakim-Raz, Noa
Turjeman, Adi
Pujol Rojo, Miquel
Carratalà, Jordi
Shaw Perujo, Evelyn
Gomila Grange, Aina
Vuong, Cuong
Addy, Ibironke
Wiegand, Irith
Grier, Sally
MacGowan, Alasdair
Vank, Christiane
van den Heuvel, Leonard
Leibovici, Leonard
author Babich, Tanya
author_facet Babich, Tanya
Eliakim-Raz, Noa
Turjeman, Adi
Pujol Rojo, Miquel
Carratalà, Jordi
Shaw Perujo, Evelyn
Gomila Grange, Aina
Vuong, Cuong
Addy, Ibironke
Wiegand, Irith
Grier, Sally
MacGowan, Alasdair
Vank, Christiane
van den Heuvel, Leonard
Leibovici, Leonard
author_role author
author2 Eliakim-Raz, Noa
Turjeman, Adi
Pujol Rojo, Miquel
Carratalà, Jordi
Shaw Perujo, Evelyn
Gomila Grange, Aina
Vuong, Cuong
Addy, Ibironke
Wiegand, Irith
Grier, Sally
MacGowan, Alasdair
Vank, Christiane
van den Heuvel, Leonard
Leibovici, Leonard
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Infeccions del tracte urinari
Factors de risc en les malalties
Risk factors in diseases
Urinary tract infections
topic Infeccions del tracte urinari
Factors de risc en les malalties
Risk factors in diseases
Urinary tract infections
description Hospital readmissions following severe infections are a major economic burden on the health care system and have a negative influence on patients' quality of life. Understanding the risk factors for readmission, particularly the extent to which they could be prevented, is of a great importance. In this study we evaluated potentially preventable risk factors for 60-day readmission in patients surviving hospitalization for complicated urinary tract infection (cUTI). This was a multinational, multicentre retrospective cohort study conducted in Europe and the Middle East. Our cohort included survivors of hospitalization due to cUTI during the years 2013-2014. The primary outcome was 60-day readmission following index hospitalization. Patient characteristics that could have influenced readmission: demographics, infection presentation and management, microbiological and clinical data; were collected via computerized medical records from infection onset up to 60 days after hospital discharge. Overall, 742 patients were included. The cohort median age was 68 years (interquartile range, (IQR) 55-80) and 43.3% (321/742) of patients were males. The all-cause 60-day readmission rate was 20.1% (149/742) and more than half were readmitted for infection [57.1%, (80/140)]. Recurrent cUTI was the most frequent cause for readmission [46.4% (65/140)]. Statistically significant risk factors associated with 60-day readmission in multivariable analysis were: older age (odds ratio (OR) 1.02 for an one-year increment, confidence interval (CI) 1.005-1.03), diabetes mellitus (OR 1.63, 95% CI 1.04-2.55), cancer (OR 1.7, 95% CI 1.05-2.77), previous urinary tract infection (UTI) in the last year (OR 1.8, 95% CI: 1.14-2.83), insertion of an indwelling bladder catheter (OR 1.62, 95% CI 1.07-2.45) and insertion of percutaneous nephrostomy (OR 3.68, 95% CI 1.67-8.13). In conclusion, patients surviving hospitalization for cUTI are frequently re-hospitalized, mostly for recurrent urinary infections associated with a medical condition that necessitated urinary interventions. Interventions to avoid re-admissions should target these patients.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/176914
url https://hdl.handle.net/2445/176914
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1038/s41598-021-86246-7
Scientific Reports, 2021, vol. 11
https://doi.org/10.1038/s41598-021-86246-7
dc.rights.none.fl_str_mv cc by (c) Babich et al., 2021
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Babich et al., 2021
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7 p.
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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