Fatal cases of bovine anaplasmosis in a herd infected with different Anaplasma marginale genotypes in southern Spain.
The genus Anaplasma contains various species capable of causing disease in animals and humans. Anaplasma marginale is one of the main tick-borne pathogens of bovines in tropical and subtropical regions; however, these bacteria are now being detected more frequently in other regions of the world incl...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Universidad de Castilla-La Mancha |
| Repositorio: | RUIdeRA. Repositorio Institucional de la UCLM |
| OAI Identifier: | oai:ruidera.uclm.es:10578/43547 |
| Acceso en línea: | https://doi.org/10.1016/j.ttbdis.2021.101864 https://hdl.handle.net/10578/43547 |
| Access Level: | acceso abierto |
| Palabra clave: | Anaplasma marginale Anaplasmosis bovina Genotipo C msp5 |
| Sumario: | The genus Anaplasma contains various species capable of causing disease in animals and humans. Anaplasma marginale is one of the main tick-borne pathogens of bovines in tropical and subtropical regions; however, these bacteria are now being detected more frequently in other regions of the world including Europe. In July 2017, abortions, mortality and morbidity in Retinta breed of cattle were investigated in southwestern Spain. Based on clinical signs, the provisional clinical diagnosis of bovine anaplasmosis was made. A molecular-phylogeneticapproach was used to characterize A. marginale using multiple markers, including 16S IRNA, msp1a, msp4 and msp5 genes. The msp1a sequence was different from the previously described sequences from Spain as wellas other countries. The isolates of A. marginale were classified as Genotype C, with two of the five tandem repeats in the amino acid sequences MSP1a being novel. The highest variability was observed in the for sequences of msp5 which was depicted in their clustering into multiple clades on a phylogenetic tree. Comparison of msp5 nucleotide sequences and the corresponding amino acid sequences revealed the co-existence of different strains in the same region. This study highlights the occurrence of clinical bovine anaplasmosis in an endemic region of Spain. |
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