Flexible genomic islands as drivers of genome evolution

Natural prokaryotic populations are composed of multiple clonal lineages that are different in their core genomes in a range that varies typically between 95 and 100% nucleotide identity. Each clonal lineage also carries a complement of not shared flexible genes that can be very large. The compounde...

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Detalhes bibliográficos
Autores: Rodríguez Valera, Francisco, Martín Cuadrado, Ana Belén, López Pérez, Mario
Formato: artículo
Fecha de publicación:2016
País:España
Recursos:Universidad Miguel Hernández de Elche
Repositorio:REDIUMH. Depósito Digital de la UMH
OAI Identifier:oai:dspace.umh.es:11000/4839
Acesso em linha:http://hdl.handle.net/11000/4839
Access Level:acceso abierto
Palavra-chave:579 - Microbiología
Descrição
Resumo:Natural prokaryotic populations are composed of multiple clonal lineages that are different in their core genomes in a range that varies typically between 95 and 100% nucleotide identity. Each clonal lineage also carries a complement of not shared flexible genes that can be very large. The compounded flexible genome provides polyclonal populations with enormous gene diversity that can be used to efficiently exploit resources. This has fundamental repercussions for interpreting individual bacterial genomes. They are better understood as parts rather than the whole. Multiple genomes are required to understand how the population interacts with its biotic and abiotic environment.