Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients

Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptiv...

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Autores: Cassol Spanemberg, Juliana, Blanco Carrión, Andrés, Rodríguez de Rivera Campillo, Ma Eugenia, Estrugo Devesa, Albert, Jané Salas, Enric, López López, José, 1958-
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/171919
Acceso en línea:https://hdl.handle.net/2445/171919
Access Level:acceso abierto
Palabra clave:Liquen pla
Manifestacions orals de les malalties
Aparell genital
Lichen planus
Oral manifestations of general diseases
Generative organs
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spelling Cutaneous, genital and oral lichen planus: a descriptive study of 274 patientsCassol Spanemberg, JulianaBlanco Carrión, AndrésRodríguez de Rivera Campillo, Ma EugeniaEstrugo Devesa, AlbertJané Salas, EnricLópez López, José, 1958-Liquen plaManifestacions orals de les malaltiesAparell genitalLichen planusOral manifestations of general diseasesGenerative organsBackground: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptive study reviewed 274 clinical histories of patients, who all presented histological confirmation of lichen planus verified by a pathologist, attending research centers in Barcelona. Results: A total of 40 LP patients (14.59%) presented genital lesions. Of 131 patients with cutaneous LP (47.8%), the most commonly affected zones were the body's flexor surfaces, representing 60.1% of cases. 24% of patients (n=55) related the start of the lesions with previous stress events. Of the 131 subjects with cutaneous lesions, 19% (n=25) also presented oral lichen planus (OLP). Of the total sample, 53.6% (n=147) of patients presented oral lesions. The systemic diseases most commonly associated with this patient sample were psychological problems such as stress, anxiety and depression (48%), hypertension (27%), gastric problems (12%), and diabetes (9.7%). A family history of lichen planus was found in only 2 cases (0,72%) out of the total of 274. Conclusions: Any patient with OLP should undergo a thorough history and examination to investigate potential extraoral manifestations. The fact that 37 patients with OLP in this patient series were identified with simultaneous involvement at more than one site highlights the need for thorough evaluation and multidisciplinary approaches to this disease.Medicina Oral SL2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/171919Articles publicats en revistes (Odontoestomatologia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.4317/medoral.22656Medicina Oral, Patología Oral y Cirugía Bucal, 2019, vol. 24, num. 1, p. 1-7https://doi.org/10.4317/medoral.22656(c) Medicina Oral SL, 2019info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1719192026-05-27T06:46:51Z
dc.title.none.fl_str_mv Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
title Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
spellingShingle Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
Cassol Spanemberg, Juliana
Liquen pla
Manifestacions orals de les malalties
Aparell genital
Lichen planus
Oral manifestations of general diseases
Generative organs
title_short Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
title_full Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
title_fullStr Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
title_full_unstemmed Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
title_sort Cutaneous, genital and oral lichen planus: a descriptive study of 274 patients
dc.creator.none.fl_str_mv Cassol Spanemberg, Juliana
Blanco Carrión, Andrés
Rodríguez de Rivera Campillo, Ma Eugenia
Estrugo Devesa, Albert
Jané Salas, Enric
López López, José, 1958-
author Cassol Spanemberg, Juliana
author_facet Cassol Spanemberg, Juliana
Blanco Carrión, Andrés
Rodríguez de Rivera Campillo, Ma Eugenia
Estrugo Devesa, Albert
Jané Salas, Enric
López López, José, 1958-
author_role author
author2 Blanco Carrión, Andrés
Rodríguez de Rivera Campillo, Ma Eugenia
Estrugo Devesa, Albert
Jané Salas, Enric
López López, José, 1958-
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Liquen pla
Manifestacions orals de les malalties
Aparell genital
Lichen planus
Oral manifestations of general diseases
Generative organs
topic Liquen pla
Manifestacions orals de les malalties
Aparell genital
Lichen planus
Oral manifestations of general diseases
Generative organs
description Background: Lichen planus (LP) is a chronic autoimmune disease that affects the oral mucosa as well as the skin, genital mucosa and other sites. Objective: to evaluate the correlation between oral, genital and cutaneous lichen planus, in a sample of LP patients. Material and methods: This descriptive study reviewed 274 clinical histories of patients, who all presented histological confirmation of lichen planus verified by a pathologist, attending research centers in Barcelona. Results: A total of 40 LP patients (14.59%) presented genital lesions. Of 131 patients with cutaneous LP (47.8%), the most commonly affected zones were the body's flexor surfaces, representing 60.1% of cases. 24% of patients (n=55) related the start of the lesions with previous stress events. Of the 131 subjects with cutaneous lesions, 19% (n=25) also presented oral lichen planus (OLP). Of the total sample, 53.6% (n=147) of patients presented oral lesions. The systemic diseases most commonly associated with this patient sample were psychological problems such as stress, anxiety and depression (48%), hypertension (27%), gastric problems (12%), and diabetes (9.7%). A family history of lichen planus was found in only 2 cases (0,72%) out of the total of 274. Conclusions: Any patient with OLP should undergo a thorough history and examination to investigate potential extraoral manifestations. The fact that 37 patients with OLP in this patient series were identified with simultaneous involvement at more than one site highlights the need for thorough evaluation and multidisciplinary approaches to this disease.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/171919
url https://hdl.handle.net/2445/171919
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.4317/medoral.22656
Medicina Oral, Patología Oral y Cirugía Bucal, 2019, vol. 24, num. 1, p. 1-7
https://doi.org/10.4317/medoral.22656
dc.rights.none.fl_str_mv (c) Medicina Oral SL, 2019
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Medicina Oral SL, 2019
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Medicina Oral SL
publisher.none.fl_str_mv Medicina Oral SL
dc.source.none.fl_str_mv Articles publicats en revistes (Odontoestomatologia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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